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Targeting B cells and plasma cells in autoimmune diseases: From established treatments to novel therapeutic approaches.
Published in:
European Journal of Immunology, 2023, v. 53, n. 1, p. 1, doi. 10.1002/eji.202149675
By:
- Merino‐Vico, Ana;
- Frazzei, Giulia;
- van Hamburg, Jan Piet;
- Tas, Sander W.
Publication type:
Article
Loss of IL-22 inhibits autoantibody formation in collagen-induced arthritis in mice.
Published in:
European Journal of Immunology, 2016, v. 46, n. 6, p. 1404, doi. 10.1002/eji.201546241
By:
- Corneth, Odilia B. J.;
- Reijmers, Rogier M.;
- Mus, Adriana M.C.;
- Asmawidjaja, Patrick S.;
- Hamburg, Jan Piet;
- Papazian, Natalie;
- Siegers, Jurre Y.;
- Mourcin, Frédéric;
- Amin, Rada;
- Tarte, Karin;
- Hendriks, Rudi W.;
- Cupedo, Tom;
- Lubberts, Erik
Publication type:
Article
Editorial for Special Issue "Advances in the Pathogenesis and Treatment of Immune-Mediated Inflammatory Diseases".
Published in:
2022
By:
- van Hamburg, Jan Piet;
- Tas, Sander W.
Publication type:
Editorial
Splenic Architecture and Function Requires Tight Control of Transmembrane TNF Expression.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 4, p. 2229, doi. 10.3390/ijms23042229
By:
- Jeucken, Kim C. M.;
- Kaaij, Merlijn H.;
- Rip, Jasper;
- van Rooijen, Charlotte C. N.;
- Kan, Yik Y.;
- Corneth, Odilia B. J.;
- van Hamburg, Jan Piet;
- Tas, Sander W.
Publication type:
Article
B Lineage Cells in ANCA-Associated Vasculitis.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 387, doi. 10.3390/ijms23010387
By:
- Merino-Vico, Ana;
- van Hamburg, Jan Piet;
- Tas, Sander W.
Publication type:
Article
Differential Contribution of NF-κB Signaling Pathways to CD4<sup>+</sup> Memory T Cell Induced Activation of Endothelial Cells.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.860327
By:
- Jeucken, Kim C. M.;
- van Rooijen, Charlotte C. N.;
- Kan, Yik Y.;
- Kocken, Lotte A.;
- Jongejan, Aldo;
- van Steen, Abraham C. I.;
- van Buul, Jaap D.;
- Olsson, Henric K.;
- van Hamburg, Jan Piet;
- Tas, Sander W.
Publication type:
Article
Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens.
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2018.02902
By:
- Fergusson, Joannah R.;
- Morgan, Michael D.;
- Bruchard, Melanie;
- Huitema, Leonie;
- Heesters, Balthasar A.;
- van Unen, Vincent;
- van Hamburg, Jan Piet;
- van der Wel, Nicole N.;
- Picavet, Daisy;
- Koning, Frits;
- Tas, Sander W.;
- Anderson, Mark S.;
- Marioni, John C.;
- Holländer, Georg A.;
- Spits, Hergen
Publication type:
Article
Human Memory Th17 Cell Populations Change Into Anti-inflammatory Cells With Regulatory Capacity Upon Exposure to Active Vitamin D.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01504
By:
- Dankers, Wendy;
- Davelaar, Nadine;
- van Hamburg, Jan Piet;
- van de Peppel, Jeroen;
- Colin, Edgar M.;
- Lubberts, Erik
Publication type:
Article
A novel 3D spheroid model of rheumatoid arthritis synovial tissue incorporating fibroblasts, endothelial cells, and macrophages.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1188835
By:
- Philippon, Eva M. L.;
- van Rooijen, Lisanne J. E.;
- Khodadust, Fatemeh;
- van Hamburg, Jan Piet;
- van der Laken, Conny J.;
- Tas, Sander W.
Publication type:
Article
CCR6<sup>+</sup> Th cell populations distinguish ACPA positive from ACPA negative rheumatoid arthritis.
Published in:
Arthritis Research & Therapy, 2015, v. 17, p. 1, doi. 10.1186/s13075-015-0800-5
By:
- Paulissen, Sandra M. J.;
- van Hamburg, Jan Piet;
- Davelaar, Nadine;
- Vroman, Heleen;
- Hazes, Johanna M. W.;
- de Jong, Pascal H. P.;
- Lubberts, Erik
Publication type:
Article
T helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?
Published in:
Arthritis Research & Therapy, 2014, v. 16, n. 2, p. 1, doi. 10.1186/ar4499
By:
- Brkic, Zana;
- Corneth, Odilia B. J.;
- van Helden-Meeuwsen, Cornelia G.;
- Dolhain, Radboud J. E. M.;
- Maria, Naomi I.;
- Paulissen, Sandra M. J.;
- Davelaar, Nadine;
- van Hamburg, Jan Piet;
- van Daele, Paul L.;
- Dalm, Virgil A.;
- van Hagen, P. Martin;
- Hazes, Johanna M. W.;
- Versnel, Marjan A.;
- Lubberts, Erik
Publication type:
Article
A Straightforward Method for 3D Visualization of B Cell Clusters and High Endothelial Venules in Lymph Nodes Highlights Differential Roles of TNFRI and -II.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.699336
By:
- Jeucken, Kim C. M.;
- Koning, Jasper J.;
- van Hamburg, Jan Piet;
- Mebius, Reina E.;
- Tas, Sander W.
Publication type:
Article
Vitamin D in Autoimmunity: Molecular Mechanisms and Therapeutic Potential.
Published in:
Frontiers in Immunology, 2017, v. 7/8, p. 1, doi. 10.3389/fimmu.2016.00697
By:
- Dankers, Wendy;
- Colin, Edgar M.;
- van Hamburg, Jan Piet;
- Lubberts, Erik
Publication type:
Article
Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease.
Published in:
Arthritis & Rheumatology, 2017, v. 69, n. 6, p. 1313, doi. 10.1002/art.40059
By:
- Corneth, Odilia B. J.;
- Verstappen, Gwenny M. P.;
- Paulissen, Sandra M. J.;
- de Bruijn, Marjolein J. W.;
- Rip, Jasper;
- Lukkes, Melanie;
- van Hamburg, Jan Piet;
- Lubberts, Erik;
- Bootsma, Hendrika;
- Kroese, Frans G. M.;
- Hendriks, Rudi W.
Publication type:
Article
A deep intronic splice–altering AIRE variant causes APECED syndrome through antisense oligonucleotide-targetable pseudoexon inclusion.
Published in:
Science Translational Medicine, 2024, v. 16, n. 765, p. 1, doi. 10.1126/scitranslmed.adk0845
By:
- Ochoa, Sebastian;
- Hsu, Amy P.;
- Oler, Andrew J.;
- Kumar, Dhaneshwar;
- Chauss, Daniel;
- van Hamburg, Jan Piet;
- van Laar, Gustaaf G.;
- Oikonomou, Vasileios;
- Ganesan, Sundar;
- Ferré, Elise M. N.;
- Schmitt, Monica M.;
- DiMaggio, Tom;
- Barber, Princess;
- Constantine, Gregory M.;
- Rosen, Lindsey B.;
- Auwaerter, Paul G.;
- Gandhi, Bhumika;
- Miller, Jennifer L.;
- Eisenberg, Rachel;
- Rubinstein, Arye
Publication type:
Article
Contribution of Type H Blood Vessels to Pathologic Osteogenesis and Inflammation in an Experimental Spondyloarthritis Model.
Published in:
Arthritis & Rheumatology, 2023, v. 75, n. 7, p. 1152, doi. 10.1002/art.42449
By:
- Kaaij, Merlijn H.;
- van Hamburg, Jan Piet;
- van Rooijen, Charlotte C. N.;
- Grüneboom, Anika;
- Kan, Yik Y.;
- Pots, Desiree;
- Schett, Georg;
- van Ruijven, Leo J.;
- van Duivenvoorde, Leonie M.;
- Huitema, Leonie F. A.;
- Baeten, Dominique L. P.;
- Tas, Sander W.
Publication type:
Article
Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathology.
Published in:
European Journal of Immunology, 2008, v. 38, n. 9, p. 2573, doi. 10.1002/eji.200737840
By:
- van Hamburg, Jan Piet;
- de Bruijn, Marjolein J. W.;
- de Almeida, Claudia Ribeiro;
- van Zwam, Marloes;
- van Meurs, Marjan;
- de Haas, Edwin;
- Boon, Louis;
- Samsom, Janneke N.;
- Hendriks, Rudi W.
Publication type:
Article
GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development.
Published in:
European Journal of Immunology, 2007, v. 37, n. 4, p. 1043, doi. 10.1002/eji.200636485
By:
- Ling, Kam-Wing;
- van Hamburg, Jan Piet;
- de Bruijn, Marjolein J. W.;
- Kurek, Dorota;
- Dingjan, Gemma M.;
- Hendriks, Rudolf W.
Publication type:
Article
The heterogeneous human memory CCR6+ T helper-17 populations differ in T-bet and cytokine expression but all activate synovial fibroblasts in an IFNγ-independent manner.
Published in:
Arthritis Research & Therapy, 2021, v. 23, n. 1, p. 1, doi. 10.1186/s13075-021-02532-9
By:
- Dankers, Wendy;
- den Braanker, Hannah;
- Paulissen, Sandra M. J.;
- van Hamburg, Jan Piet;
- Davelaar, Nadine;
- Colin, Edgar M.;
- Lubberts, Erik
Publication type:
Article

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