We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
SARS-CoV-2 Infection and the COVID-19 Pandemic Emergency: The Importance of Diagnostic Methods.
- Authors
Ciotti, Marco; Benedetti, Francesca; Zella, Davide; Angeletti, Silvia; Ciccozzi, Massimo; Bernardini, Sergio
- Abstract
Background: Currently, a pandemic of coronavirus disease 2019 (COVID-19) caused by the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is underway, resulting in high morbidity and mortality across the globe. Summary: A prompt and effective diagnosis is crucial to identify infected individuals, to monitor the infection, to perform contact tracing, and to limit the spread of the virus. Since the announcement of this public health emergency, several diagnostic methods have been developed including molecular and serological assays, and more recently biosensors. Here, we present the use of these assays as well as their main technical features, advantages, and limits. Key Messages: The development of reliable diagnostic assays is crucial not only for a correct diagnosis and containment of COVID-19 pandemic, but also for the decision-making process that is behind the clinical decisions, eventually contributing to the improvement of patient management. Furthermore, with the advent of vaccine and therapeutic monoclonal antibodies against SARS-CoV-2, serological assays will be instrumental for the validation of these new therapeutic options.
- Subjects
COVID-19; COVID-19 pandemic; SARS-CoV-2; VIRAL transmission; CONTACT tracing
- Publication
Chemotherapy (0009-3157), 2021, Vol 66, Issue 1/2, p17
- ISSN
0009-3157
- Publication type
Article
- DOI
10.1159/000515343