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A multi-biomarker micronucleus assay using imaging flow cytometry.
Published in:
Archives of Toxicology, 2024, v. 98, n. 9, p. 3137, doi. 10.1007/s00204-024-03801-7
By:
- Harte, Danielle S. G.;
- Lynch, Anthony M.;
- Verma, Jatin;
- Rees, Paul;
- Filby, Andrew;
- Wills, John W.;
- Johnson, George E.
Publication type:
Article
International Pig-a gene mutation assay trial: Evaluation of transferability across 14 laboratories.
Published in:
Environmental & Molecular Mutagenesis, 2011, v. 52, n. 9, p. 690, doi. 10.1002/em.20672
By:
- Dertinger, Stephen D.;
- Phonethepswath, Souk;
- Weller, Pamela;
- Nicolette, John;
- Murray, Joel;
- Sonders, Paul;
- Vohr, Hans-Werner;
- Shi, Jing;
- Krsmanovic, Ljubica;
- Gleason, Carol;
- Custer, Laura;
- Henwood, Andrew;
- Sweder, Kevin;
- Stankowski, Leon F.;
- Roberts, Daniel J.;
- Giddings, Amanda;
- Kenny, Julia;
- Lynch, Anthony M.;
- Defrain, Céline;
- Nesslany, Fabrice
Publication type:
Article
International Pig-a gene mutation assay trial (Stage III): Results with N-methyl- N-nitrosourea.
Published in:
Environmental & Molecular Mutagenesis, 2011, v. 52, n. 9, p. 699, doi. 10.1002/em.20691
By:
- Lynch, Anthony M.;
- Giddings, Amanda;
- Custer, Laura;
- Gleason, Carol;
- Henwood, Andrew;
- Aylott, Mike;
- Kenny, Julia
Publication type:
Article
New and emerging technologies for genetic toxicity testing.
Published in:
Environmental & Molecular Mutagenesis, 2011, v. 52, n. 3, p. 205, doi. 10.1002/em.20614
By:
- Lynch, Anthony M.;
- Sasaki, Jennifer C.;
- Elespuru, Rosalie;
- Jacobson-Kram, David;
- Thybaud, Véronique;
- De Boeck, Marlies;
- Aardema, Marilyn J.;
- Aubrecht, Jiri;
- Benz, R. Daniel;
- Dertinger, Stephen D.;
- Douglas, George R.;
- White, Paul A.;
- Escobar, Patricia A.;
- Fornace, Albert;
- Honma, Masamitsu;
- Naven, Russell T.;
- Rusling, James F.;
- Schiestl, Robert H.;
- Walmsley, Richard M.;
- Yamamura, Eiji
Publication type:
Article
Interlaboratory validation of a CD71-based flow cytometric method (Microflow) for the scoring of micronucleated reticulocytes in mouse peripheral blood.
Published in:
Environmental & Molecular Mutagenesis, 2005, v. 45, n. 1, p. 44
By:
- Dorothea K. Torous;
- Nikki E. Hall;
- Anne H. Illi-Love;
- Marilyn S. Diehl;
- Karin Cederbrant;
- Kerstin Sandelin;
- Ingrid Pontn;
- George Bolcsfoldi;
- Lynnette R. Ferguson;
- Amira Pearson;
- Jenness B. Majeska;
- James P. Tarca;
- Geoffrey M. Hynes;
- Anthony M. Lynch;
- James P. McNamee;
- Pascale V. Bellier;
- Monique Parenteau;
- David Blakey;
- Janet Bayley;
- Bas-Jan M. van der Leede
Publication type:
Article
Analysis of gene mutations and clastogenicity following short-term treatment with azathioprine in Muta™Mouse.
Published in:
Environmental & Molecular Mutagenesis, 1999, v. 34, n. 2/3, p. 131, doi. 10.1002/(SICI)1098-2280(1999)34:2/3<131::AID-EM12>3.0.CO;2-K
By:
- Smith, Catherine C.;
- Archer, Graeme E.;
- Forster, Emma J.;
- Lambert, T. Richard;
- Rees, Robert W.;
- Lynch, Anthony M.
Publication type:
Article
Flow Cytometric Analysis of Micronuclei in Peripheral Blood Reticulocytes III. An Efficient Method of Monitoring Chromosomal Damage in the Beagle Dog.
Published in:
Toxicological Sciences, 2007, v. 100, n. 2, p. 406, doi. 10.1093/toxsci/kfm241
By:
- Harper, Susan B.;
- Dertinger, Stephen D.;
- Bishop, Michelle E.;
- Lynch, Anthony M.;
- Lorenzo, Maria;
- Saylor, Michelle;
- MacGregor, James T.
Publication type:
Article
Cycloheximide and disulfoton are positive in the photoclastogencity assay but do not absorb UV irradiation: another example of pseudophotoclastogenicity?
Published in:
Mutagenesis, 2008, v. 23, n. 2, p. 111, doi. 10.1093/mutage/gem053
By:
- Anthony M. Lynch;
- Sharon A. Robinson;
- Phil Wilcox;
- Mark D. Smith;
- Mark Kleinman;
- Kaina Jiang;
- Robert W. Rees
Publication type:
Article
The results of five coded compounds: genistein, metaproterenol, rotenone, p-anisidine and resorcinol tested in the pH 6.7 Syrian hamster embryo cell morphological transformation assay.
Published in:
Mutagenesis, 2005, v. 20, n. 1, p. 51, doi. 10.1093/mutage/gei009
By:
- James S. Harvey;
- Jonathan R. Howe;
- Anthony M. Lynch;
- Robert W. Rees
Publication type:
Article
DNA damage responses after exposure to DNA-based products.
Published in:
Journal of Gene Medicine, 2006, v. 8, n. 2, p. 175, doi. 10.1002/jgm.827
By:
- Smith, Catherine C.;
- Aylott, Michael C.;
- Fisher, Krishna J.;
- Lynch, Anthony M.;
- Gooderham, Nigel J.
Publication type:
Article
Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning.
Published in:
Archives of Toxicology, 2021, v. 95, n. 9, p. 3101, doi. 10.1007/s00204-021-03113-0
By:
- Wills, John W.;
- Verma, Jatin R.;
- Rees, Benjamin J.;
- Harte, Danielle S. G.;
- Haxhiraj, Qiellor;
- Barnes, Claire M.;
- Barnes, Rachel;
- Rodrigues, Matthew A.;
- Doan, Minh;
- Filby, Andrew;
- Hewitt, Rachel E.;
- Thornton, Catherine A.;
- Cronin, James G.;
- Kenny, Julia D.;
- Buckley, Ruby;
- Lynch, Anthony M.;
- Carpenter, Anne E.;
- Summers, Huw D.;
- Johnson, George E.;
- Rees, Paul
Publication type:
Article
N-Nitrosodimethylamine investigations in Muta™Mouse define point-of-departure values and demonstrate less-than-additive somatic mutant frequency accumulations.
Published in:
Mutagenesis, 2024, v. 39, n. 2, p. 96, doi. 10.1093/mutage/geae001
By:
- Lynch, Anthony M;
- Howe, Jonathan;
- Hildebrand, Deon;
- Harvey, James S;
- Burman, Mark;
- Harte, Danielle S G;
- Chen, Liangfu;
- Kmett, Casey;
- Shi, Wei;
- McHugh, Charles F;
- Patel, Kinnari K;
- Junnotula, Venkat;
- Kenny, Julia;
- Haworth, Richard;
- Wills, John W
Publication type:
Article
Ames test study designs for nitrosamine mutagenicity testing: qualitative and quantitative analysis of key assay parameters.
Published in:
Mutagenesis, 2024, v. 39, n. 2, p. 78, doi. 10.1093/mutage/gead033
By:
- Thomas, Dean N;
- Wills, John W;
- Tracey, Helen;
- Baldwin, Sandy J;
- Burman, Mark;
- Williams, Abbie N;
- Harte, Danielle S G;
- Buckley, Ruby A;
- Lynch, Anthony M
Publication type:
Article
Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology.
Published in:
Mutagenesis, 2023, v. 38, n. 4, p. 192, doi. 10.1093/mutage/gead012
By:
- Lynch, Anthony M;
- Zanoni, Thalita B;
- Salk, Jesse J;
- Martincorena, Inigo;
- Young, Robert R;
- Kucab, Jill;
- Valentine, Charles C;
- Yauk, Carole;
- Escobar, Patricia A;
- Witt, Kristine L;
- Frötschl, Roland;
- Reed, Simon H;
- Ashford, Anne
Publication type:
Article
Development of an in vitro PIG-A gene mutation assay in human cells.
Published in:
Mutagenesis, 2017, v. 32, n. 2, p. 283, doi. 10.1093/mutage/gew059
By:
- Rees, Benjamin J.;
- Tate, Matthew;
- Lynch, Anthony M.;
- Thornton, Catherine A.;
- Jenkins, Gareth J.;
- Walmsley, Richard M.;
- Johnson, George E.
Publication type:
Article
Genotoxicity assessment of peptide/ protein-related biotherapeutics: points to consider before testing.
Published in:
Mutagenesis, 2016, v. 31, n. 4, p. 375, doi. 10.1093/mutage/gew013
By:
- Thybaud, Veronique;
- Kasper, Peter;
- Sobol, Zhanna;
- Elhajouji, Azeddine;
- Fellows, Mick;
- Guerard, Melanie;
- Lynch, Anthony M.;
- Sutter, Andreas;
- Tanir, Jennifer Y.
Publication type:
Article
Evaluating the genotoxicity of topoisomerase-targeted antibiotics.
Published in:
Mutagenesis, 2012, v. 27, n. 3, p. 359, doi. 10.1093/mutage/ger089
By:
- Smart, Daniel J.;
- Lynch, Anthony M.
Publication type:
Article
The in vivo rat skin photomicronucleus assay: phototoxicity and photogenotoxicity evaluation of six fluoroquinolones.
Published in:
Mutagenesis, 2012, v. 27, n. 6, p. 721, doi. 10.1093/mutage/ges038
By:
- Reus, Astrid A.;
- Usta, Mustafa;
- Kenny, Julia D.;
- Clements, Peter J.;
- Pruimboom-Brees, Ingrid;
- Aylott, Mike;
- Lynch, Anthony M.;
- Krul, Cyrille A.M
Publication type:
Article
Development and characterization of an in vivo skin photomicronucleus assay in rats.
Published in:
Mutagenesis, 2010, v. 25, n. 4, p. 407, doi. 10.1093/mutage/geq023
By:
- Reus, Astrid A.;
- Usta, Mustafa;
- van Meeuwen, Richard N. C.;
- Maas, Wilfred J. M.;
- Robinson, Sharon A.;
- Kenny, Julia D.;
- Pruimboom-Brees, Ingrid;
- Clements, Peter J.;
- Lynch, Anthony M.;
- Krul, Cyrille A. M.
Publication type:
Article
Analysis of 75 marketed pharmaceuticals using the GADD45a-GFP ‘GreenScreen HC’ genotoxicity assay.
Published in:
Mutagenesis, 2009, v. 24, n. 5, p. 455, doi. 10.1093/mutage/gep029
By:
- Hastwell, Paul W.;
- Webster, Thomas W.;
- Tate, Matthew;
- Billinton, Nicholas;
- Lynch, Anthony M.;
- Harvey, James S.;
- Rees, Robert W.;
- Walmsley, Richard M.
Publication type:
Article
Early events in the mammalian response to DNA double-strand breaks.
Published in:
Mutagenesis, 2008, v. 23, n. 5, p. 331, doi. 10.1093/mutage/gen039
By:
- Lucy C. Riches;
- Anthony M. Lynch;
- Nigel J. Gooderham
Publication type:
Article

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