We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Hyperthermia and radiation therapy in the treatment of recurrent Merkel cell tumors.
- Authors
Knox, Susan J.; Kapp, Daniel S.; Knox, S J; Kapp, D S
- Abstract
A high incidence of local recurrence, spread to regional lymph nodes, and distant metastases has been reported after surgical excision of Merkel cell tumors (MCT). The use of postoperative radiation therapy and/or chemotherapy is reviewed from the literature. Despite adjuvant treatment, local tumor recurrences frequently develop. Two patients are presented with metastatic MCT recurrent in previously irradiated sites who had excellent clinical responses and local control following retreatment with local hyperthermia in conjunction with low to moderate dose radiation therapy. These patients represent the first reported use of hyperthermia in the management of MCT. The encouraging local responses described suggest a potential role for the use of hyperthermia and concomitant radiation therapy in the treatment of recurrent MCT.
- Publication
Cancer (0008543X), 1988, Vol 62, Issue 8, p1479
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19881015)62:8<1479::AID-CNCR2820620806>3.0.CO;2-H