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- Title
Estrogen receptor values in patients with benign breast disease.
- Authors
Allegra, Joseph C.; Lippman, Marc E.; Green, Linda; Barlock, Audrey; Simon, Richard; Thompson, E. B.; Huff, Karen K.; Griffin, Walter; Allegra, J C; Lippman, M E; Green, L; Barlock, A; Simon, R; Huff, K K; Griffin, W
- Abstract
Tissue specimens from 55 female patients with benign breast disease were assayed for estrogen receptor. Twenty-one of 55 patients (38%) had tumors which contained significant amounts of estrogen receptor (greater than 10 femtomoles/mg protein). Fibroadenomas possessed estrogen receptor more frequently than fibrocystic disease or other benign breast tumors. Estrogen receptor positivity did not correlate with laterality of the tumor; location or size of the largest nodule. Patients with estrogen receptor positive tumors had a mean age of 26.9 years compared to 36.4 years for patients with estrogen receptor negative tumors (p less than 0.01). Twenty of 46 (43%) premenopausal patients had benign tumors which were estrogen receptor positive compared to zero of 8 postmenopausal patients (p less than 0.05).
- Publication
Cancer (0008543X), 1979, Vol 44, Issue 1, p228
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(197907)44:1<228::AID-CNCR2820440137>3.0.CO;2-0