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- Title
Tissue-Engineered Cultured Periosteum Sheet Application to Treat Infrabony Defects: Case Series and 5-Year Results.
- Authors
Okuda, Kazuhiro; Kawase, Tomoyuki; Nagata, Masaki; Yamamiya, Kanoko; Nakata, Koh; Wolff, Larry F.; Yoshie, Hiromasa
- Abstract
One-year data after autologous grafting of infrabony periodontal defects with human cultured periosteum sheets in combination with platelet-rich plasma and hydroxyapatite granules have shown favorable clinical and radiographic results. A 5-year follow-up evaluation of 22 selected patients indicated that treated infrabony defects remained stable. Radiographically, there was an increase in osseous radiopacity and bone trabeculation suggesting further bone maturation. This novel tissue-engineered periodontal treatment approach has resulted in significant clinical improvement, and defects remained stable after 5 years.
- Subjects
PERIODONTAL disease treatment; LONGITUDINAL method; MINERALS; HEALTH outcome assessment; PERIOSTEUM; RESEARCH funding; STATISTICS; TRANSPLANTATION of organs, tissues, etc.; DATA analysis; TISSUE engineering; TREATMENT effectiveness; DESCRIPTIVE statistics; PLATELET-rich plasma
- Publication
International Journal of Periodontics & Restorative Dentistry, 2013, Vol 33, Issue 3, p280
- ISSN
0198-7569
- Publication type
Article
- DOI
10.11607/prd.1545