We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Extensive N-methylation of chitosan: evaluating the effects of the reaction conditions by using response surface methodology.
- Authors
Senra, Tonimar DA; Santos, Danilo M; Desbrières, Jacques; Campana ‐ Filho, Sergio P
- Abstract
The effects of reaction time, concentration of aqueous sodium hydroxide and molar ratio iodomethane/chitosan on the yield of the reaction of chitosan with iodomethane in N-methyl-2-pyrrolidone ( NMP) at 25.0 ± 0.1 °C, as well as on the characteristics of the resulting N, N, N-trimethylchitosan ( TMCh), were evaluated by using full-factorial 23 design analysis and response surface methodology. This study also aimed to determine the reaction conditions allowing the production of water-soluble TMCh presenting a high average degree of quaternization and intrinsic viscosity at high reaction yield. 1H NMR spectroscopy was employed for structural characterization, including the determination of average degrees of acetylation (
- Subjects
REACTION time; SODIUM hydroxide; METHYL iodide; CHITOSAN; RESPONSE surfaces (Statistics); METHYLATION; CHEMICAL yield; NUCLEAR magnetic resonance spectroscopy
- Publication
Polymer International, 2015, Vol 64, Issue 11, p1617
- ISSN
0959-8103
- Publication type
Article
- DOI
10.1002/pi.4962