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- Title
Homogeneous interferon-inducing 22K factor is related to endogenous pyrogen and interleukin-1.
- Authors
Van Damme, J.; De Ley, M.; Openakker, G.; Billiau, A.; De Somer, P.; Van Beeumen, J.
- Abstract
The article describes the analysis of the interferon-inducing factor 22K from human peripheral mononuclear cells with polyacrylamide gel electrophoresis. The biological properties of 22K included antiviral activity and the induction of fever and granulopenia, suggesting that the factor is related to endogenous pyrogen (EP) and lymphocyte-activating factor (LAF) and is a member of the interleukin-1 (IL-1) family of monokines.
- Subjects
MONONUCLEAR leukocytes; MONOKINES; INTERFERONS; INTERLEUKIN-1; FEVER; GRANULOCYTOPENIA; PYROGENS; POLYACRYLAMIDE gel electrophoresis
- Publication
Nature, 1985, p266
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/314266a0