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- Title
Flavanol-Rich Cocoa Supplementation Inhibits Mitochondrial Biogenesis Triggered by Exercise.
- Authors
García-Merino, Jose Angel; de Lucas, Beatriz; Herrera-Rocha, Karen; Moreno-Pérez, Diego; Montalvo-Lominchar, Maria Gregoria; Fernández-Romero, Arantxa; Santiago, Catalina; Pérez-Ruiz, Margarita; Larrosa, Mar
- Abstract
HCO: untrained group receiving high-dose cocoa at 24.6 mg/kg b.w.; CONTEx: control exercise-trained group; COEx: exercise-trained group supplemented with cocoa at 8.2 mg/kg; HCOEx: exercise-trained group supplemented with high-dose cocoa at 24.6 mg/kg b.w. The performance of an exercise bout led to an elevation in oxidative stress, as supported by the TBARS and SOD data, and this was attenuated after 10 weeks in the both CT and CO groups by the practice of physical exercise and the increased physical condition, as expected [[47]], but this was more marked in athletes supplemented with cocoa, which may diminish the adaptations to exercise [[48]]. The period in which the supplementation occurred, during which time great adaptations to exercise were taking place, the framework of the athletes' diets, which were rich in fruits and vegetables, and the type of cocoa used in the study, could be determining factors in the observed effects of cocoa on athletes. (CO), (3) untrained group receiving high-dose cocoa at 24.6 mg/kg b.w (HCO), (4) control exercise-trained group (CONTEx), (5) exercise-trained group supplemented with cocoa at 8.2 mg/kg b.w.
- Subjects
ANAEROBIC threshold; MITOCHONDRIAL DNA; AEROBIC capacity; NUCLEAR factor E2 related factor; COCOA
- Publication
Antioxidants, 2022, Vol 11, Issue 8, pN.PAG
- ISSN
2076-3921
- Publication type
Article
- DOI
10.3390/antiox11081522