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- Title
C-05 Influence of Depression on Neuropsychological Performance of Returning Veterans With or Without Posttraumatic Stress Disorder.
- Authors
Raymond, M; Paxton, J; Weaver, S; Deluca, J
- Abstract
Objective: The purpose of this study was to determine the influence of depression and posttraumatic stress disorder (PTSD) on neuropsychological performance of returning Veterans. Method: Data were utilized from 138 returning Veterans who were either diagnosed with or without PTSD and who had completed a neuropsychological evaluation. Results: A 2 x 2 analysis of covariance (ANCOVA) of the General Memory Index (GMI) scores of the Wechsler Memory Scale III with age as a covariate and PTSD group (PTSD vs. non-PTSD) and depressive classifications (depressed vs. not depressed) as between subject variables was conducted. A main effect of PTSD, F(1, 333) = 4.01, p = .05, demonstrated that GMI scores were higher in the PTSD (M = 97.48) compared with the non-PTSD group (M = 92.48). A significant main effect of depression was uncovered, F(1, 133) = 9.36, p < .01 with depressed Veterans (M = 90.72) demonstrating lower scores compared with non-depressed veterans (M = 98.08). A significant interaction between depression and PTSD group, F(1, 133) = 4.75, p < .05 was noted. In follow-up contrasts, GMI scores were significantly lower in non-PTSD Veterans with depression (M = 85.92) compared with PTSD Veterans with depression, t(80) = 3.87, p < .001. Conclusion(s): These results suggest that depressive symptoms may have less of an effect on neuropsychological performance in Veterans with PTSD. These results highlight the importance of considering depressive symptoms when assessing neuropsychological performance in Veterans and may have implications for the development of specific treatment strategies as well as future studies.Between-Subjects FactorsValue LabelNdepression_group.00T < 65711.00T > 6567PTSD_NUM.00noptsd821.00Ptsd56Descriptive StatisticsDependent Variable: WMS_gen_memdepression_groupPTSD_NUMMeanStd. DeviationNT < 65noptsd97.6114.02946ptsd98.9611.17125Total98.0813.02871T > 65noptsd85.9212.98236ptsd96.2914.32831Total90.7214.48667Totalnoptsd92.4814.70682ptsd97.4812.97056Total94.5114.194138Tests of Between-Subjects EffectsDependent Variable: WMS_gen_memSourceType III Sum of SquaresdfMean SquareFSig.Partial Eta SquaredCorrected Model4954.388a41238.5977.274.000.179Intercept179475.3691179475.3691053.961.000.888Age1260.94911260.9497.405.007.053depression_group1594.52811594.5289.364.003.066PTSD_NUM682.9021682.9024.010.047.029depression_group * PTSD_NUM808.1751808.1754.746.031.034Error22648.105133170.287Total1260166.000138Corrected Total27602.493137a. R Squared = .179 (Adjusted R Squared = .155)
- Subjects
MENTAL depression; NEUROPSYCHOLOGICAL tests; POST-traumatic stress disorder; MEMORY testing; DISEASES in veterans; DESCRIPTIVE statistics; CLINICAL neuropsychology
- Publication
Archives of Clinical Neuropsychology, 2014, Vol 29, Issue 6, p573
- ISSN
0887-6177
- Publication type
Article
- DOI
10.1093/arclin/acu038.186