We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
RBANS Memory Indices Are Related to Medial Temporal Lobe Volumetrics in Healthy Older Adults and Those with Mild Cognitive Impairment.
- Authors
England, Heather B.; Gillis, M. Meredith; Hampstead, Benjamin M.
- Abstract
The current study (i) determined whether NeuroQuant® volumetrics are reflective of differences in medial temporal lobe (MTL) volumes between healthy older adults and those with mild cognitive impairment (MCI) and (ii) examined the relationship between RBANS indices and MTL volumes. Forty-three healthy older adults and 57 MCI patients completed the RBANS and underwent structural MRI. Hippocampal and inferior lateral ventricle (ILV) volumes were obtained using NeuroQuant®. Results revealed significantly smaller hippocampal and larger ILV volumes in MCI patients. MTL volumes were significantly related to the RBANS Immediate and Delayed Memory and Language indices but not the Attention or Visuoconstruction indices; findings that demonstrate anatomical specificity. Following discriminant function analysis, we calculated a cutpoint that may prove clinically useful for integrating MTL volumes into the diagnosis of MCI. These findings demonstrate the potential clinical utility of NeuroQuant® and are the first to document the relationship between RBANS indices and MTL volumes.
- Subjects
MILD cognitive impairment; TEMPORAL lobe; DISEASES in older people; MAGNETIC resonance imaging of the brain; MEMORY testing; CLINICAL trials; DIAGNOSIS
- Publication
Archives of Clinical Neuropsychology, 2014, Vol 29, Issue 4, p322
- ISSN
0887-6177
- Publication type
Article
- DOI
10.1093/arclin/acu012