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- Title
STAT3 mutations are highly specific for large granular lymphocytic leukemia.
- Authors
Fasan, A; Kern, W; Grossmann, V; Haferlach, C; Haferlach, T; Schnittger, S
- Abstract
The article presents a study which determines high specific STAT3 mutations for large granular lymphocytic leukemia. The study analyzed and compared the frequency and potential prognostic impact of STAT3 mutations in 56 patients with large granular lymphocytic (T-LGL) leukemia and cases with other T-cell malignancies and reactive conditions. Results of the study confirmed the presence of STAT3 mutations in T-LGL higher frequency of 72.7%.
- Subjects
LYMPHOCYTIC leukemia; T cells; PROGNOSIS; LYMPHOPROLIFERATIVE disorders; LYMPHOCYTES
- Publication
Leukemia (08876924), 2013, Vol 27, Issue 7, p1598
- ISSN
0887-6924
- Publication type
Article
- DOI
10.1038/leu.2012.350