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- Title
Immobilization hypercalcaemia responding to intravenous pamidronate sodium therapy.
- Authors
McIntyre, H. D.; Cameron, D. P.; Urquhart, S. M.; Davies, W. E.
- Abstract
A 16 year old male developed symptomatic hypercalcaemia of immobilization on day 47 following a diving accident which had resulted in incomplete C4 tetraplegia. Following initial reduction in serum calcium with salmon calcitonin 100 U/day, symptomatic hypercalcaemia recurred. A single dose of 30 mg pamidronate sodium, given intravenously, caused serum calcium to fall within 48 hours. Initial mild, asymptomatic hypocalcaemia was followed by a return to sustained normocalcaemia. No major adverse reaction was encountered, and if further clinical experience confirms its efficacy, pamidronate sodium will warrant consideration as first-line therapy for immobilization hypercalcaemia.
- Subjects
DIPHOSPHONATES; HYPERCALCEMIA; INTRAVENOUS therapy
- Publication
Postgraduate Medical Journal, 1989, Vol 65, Issue 762, p244
- ISSN
0032-5473
- Publication type
journal article