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Translational pharmacokinetic modelling and simulation for the assessment of duration of contraceptive use after treatment with miltefosine.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2012, v. 67, n. 8, p. 1996, doi. 10.1093/jac/dks164
By:
- Dorlo, Thomas P. C.;
- Balasegaram, Manica;
- Lima, María Angeles;
- de Vries, Peter J.;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.
Publication type:
Article
Use of dried blood spots for the determination of plasma concentrations of nevirapine and efavirenz.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2012, v. 67, n. 5, p. 1211, doi. 10.1093/jac/dks011
By:
- Kromdijk, Wiete;
- Mulder, Jan W.;
- Rosing, Hilde;
- Smit, Patrick M.;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.
Publication type:
Article
Editorial: Therapeutic Drug Monitoring (TDM): A Useful Tool for Pediatric Pharmacology Applied to Routine Clinical Practice.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.931843
By:
- Simeoli, Raffaele;
- Dorlo, Thomas P. C.;
- Hanff, Lidwien M.;
- Huitema, Alwin D. R.;
- Dreesen, Erwin
Publication type:
Article
Effect of Food on the Pharmacokinetics of the Oral Docetaxel Tablet Formulation ModraDoc006 Combined with Ritonavir (ModraDoc006/r) in Patients with Advanced Solid Tumours.
Published in:
Drugs in R&D, 2021, v. 21, n. 1, p. 103, doi. 10.1007/s40268-020-00336-x
By:
- Vermunt, Marit A. C.;
- de Weger, Vincent A.;
- Janssen, Julie M.;
- Lopez-Yurda, Marta I.;
- Keessen, Marianne;
- Thijssen, Bas;
- Rosing, Hilde;
- Huitema, Alwin D. R.;
- Beijnen, Jos H.;
- Marchetti, Serena
Publication type:
Article
Should Non-Nucleoside Reverse Transcriptase Inhibitors be Combined?
Published in:
Drugs in R&D, 2005, v. 6, n. 2, p. 61, doi. 10.2165/00126839-200506020-00001
By:
- Kappelhoff, Bregt S.;
- Huitema, Alwin D. R.;
- Beijnen, Jos H.
Publication type:
Article
Optimization of a Quantitative Anti-Drug Antibodies against Infliximab Assay with the Liquid Chromatography-Tandem Mass Spectrometry: A Method Validation Study and Future Perspectives.
Published in:
Pharmaceutics, 2023, v. 15, n. 5, p. 1477, doi. 10.3390/pharmaceutics15051477
By:
- Smeijsters, Erin H.;
- van der Elst, Kim C. M.;
- Visch, Amy;
- Göbel, Camiel;
- Loeff, Floris C.;
- Rispens, Theo;
- Huitema, Alwin D. R.;
- van Luin, Matthijs;
- El Amrani, Mohsin
Publication type:
Article
Practical Recommendations for the Manipulation of Kinase Inhibitor Formulations to Age-Appropriate Dosage Forms.
Published in:
Pharmaceutics, 2022, v. 14, n. 12, p. 2834, doi. 10.3390/pharmaceutics14122834
By:
- Bernsen, Emma C.;
- Hogenes, Valery J.;
- Nuijen, Bastiaan;
- Hanff, Lidwien M.;
- Huitema, Alwin D. R.;
- Diekstra, Meta H. M.
Publication type:
Article
Predictiveness of the Human-CYP3A4-Transgenic Mouse Model (Cyp3aXAV) for Human Drug Exposure of CYP3A4-Metabolized Drugs.
Published in:
Pharmaceuticals (14248247), 2022, v. 15, n. 7, p. N.PAG, doi. 10.3390/ph15070860
By:
- Damoiseaux, David;
- Li, Wenlong;
- Martínez-Chávez, Alejandra;
- Beijnen, Jos H.;
- Schinkel, Alfred H.;
- Huitema, Alwin D. R.;
- Dorlo, Thomas P. C.
Publication type:
Article
Adherence to low-dose methotrexate in children with juvenile idiopathic arthritis using a sensitive methotrexate assay.
Published in:
Pediatric Rheumatology, 2024, v. 22, p. 1, doi. 10.1186/s12969-024-00988-y
By:
- Möhlmann, Julia E.;
- de Roock, Sytze;
- Egas, Annelies C.;
- Weijden, Evelien ter;
- Doeleman, Martijn J. H.;
- Huitema, Alwin D. R.;
- van Luin, Matthijs;
- Swart, Joost F.
Publication type:
Article
The influence of body mass index on the tolerability and effectiveness of full-weight-based paclitaxel chemotherapy in women with early-stage breast cancer.
Published in:
Breast Cancer Research & Treatment, 2022, v. 195, n. 3, p. 325, doi. 10.1007/s10549-022-06681-6
By:
- Lin, Lishi;
- Soesan, Marcel;
- van Balen, Dorieke E. M.;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.
Publication type:
Article
Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting.
Published in:
Supportive Care in Cancer, 2022, v. 30, n. 12, p. 9991, doi. 10.1007/s00520-022-07423-6
By:
- Nijstad, A. Laura;
- de Vos-Kerkhof, Evelien;
- Enters-Weijnen, Catherine F.;
- van de Wetering, Marianne D.;
- Tissing, Wim J. E.;
- Tibben, Matthijs M.;
- Rosing, Hilde;
- Lalmohamed, Arief;
- Huitema, Alwin D. R.;
- Zwaan, C. Michel
Publication type:
Article
The Predictive Value of Low Skeletal Muscle Mass Assessed on Cross-Sectional Imaging for Anti-Cancer Drug Toxicity: A Systematic Review and Meta-Analysis.
Published in:
Journal of Clinical Medicine, 2020, v. 9, n. 11, p. 3780, doi. 10.3390/jcm9113780
By:
- Huiskamp, Laura F. J.;
- Chargi, Najiba;
- Devriese, Lot A.;
- May, Anne M.;
- Huitema, Alwin D. R.;
- de Bree, Remco
Publication type:
Article
Automated radiolabelling of [68Ga]Ga-PSMA-11 (gallium (68Ga)-gozetotide) using the Locametz® kit and two generators.
Published in:
EJNMMI Radiopharmacy & Chemistry, 2024, v. 9, n. 1, p. 1, doi. 10.1186/s41181-024-00260-4
By:
- van Brandwijk, Elke A.;
- Aalbersberg, Else A.;
- Hosseini, Arman S.;
- Huitema, Alwin D. R.;
- Hendrikx, Jeroen J. M. A.
Publication type:
Article
Corrigendum to “Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy”.
Published in:
BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/124035
By:
- van Hasselt, J. G. Coen;
- Allegaert, Karel;
- van Calsteren, Kristel;
- Beijnen, Jos H.;
- Schellens, Jan H. M.;
- Huitema, Alwin D. R.
Publication type:
Article
Persistent neuropathy after treatment with cisplatin and oxaliplatin.
Published in:
Acta Oncologica, 2009, v. 48, n. 6, p. 832, doi. 10.1080/02841860902806609
By:
- BROUWERS, ELKE E. M.;
- HUITEMA, ALWIN D. R.;
- BOOGERD, WILLEM;
- BEIJNEN, JOS H.;
- SCHELLENS, JAN H. M.
Publication type:
Article
Pharmacokinetics of PEGasparaginase in Infants with Acute Lymphoblastic Leukemia.
Published in:
Pharmaceutical Research, 2024, v. 41, n. 4, p. 711, doi. 10.1007/s11095-024-03693-3
By:
- Brigitha, Leiah J.;
- Mondelaers, Veerle;
- Liu, Yiwei;
- Albertsen, Birgitte K.;
- Zalewska-Szewczyk, Beata;
- Rizzari, Carmelo;
- Kotecha, Rishi S.;
- Pieters, Rob;
- Huitema, Alwin D. R.;
- van der Sluis, Inge M.
Publication type:
Article
Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate.
Published in:
Pharmaceutical Research, 2023, v. 40, n. 12, p. 3001, doi. 10.1007/s11095-023-03615-9
By:
- Bruin, Maaike A. C.;
- Mohmaed Ali, Ma Ida;
- van Nuland, Merel;
- Jacobs, Bart A. W.;
- Lucas, Luc;
- Dezentje, Vincent O.;
- de Feijter, Jeantine M.;
- Rosing, Hilde;
- Bergman, Andries M.;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.
Publication type:
Article
Exposure–Response Analyses of Olaparib in Real-Life Patients with Ovarian Cancer.
Published in:
Pharmaceutical Research, 2023, v. 40, n. 5, p. 1239, doi. 10.1007/s11095-023-03497-x
By:
- Mohmaed Ali, Ma Ida;
- Bruin, Maaike A. C.;
- Dezentjé, Vincent O.;
- Beijnen, Jos H.;
- Steeghs, Neeltje;
- Huitema, Alwin D. R.
Publication type:
Article
A Population Pharmacokinetic Modelling Approach to Unravel the Complex Pharmacokinetics of Vincristine in Children.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 10, p. 2487, doi. 10.1007/s11095-022-03364-1
By:
- Nijstad, A. Laura;
- Chu, Wan-Yu;
- de Vos-Kerkhof, Evelien;
- Enters-Weijnen, Catherine F.;
- van de Velde, Mirjam E.;
- Kaspers, Gertjan J. L.;
- Barnett, Shelby;
- Veal, Gareth J.;
- Lalmohamed, Arief;
- Zwaan, C. Michel;
- Huitema, Alwin D. R.
Publication type:
Article
Exposure–Response Analysis of Osimertinib in EGFR Mutation Positive Non-Small Cell Lung Cancer Patients in a Real-Life Setting.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 10, p. 2507, doi. 10.1007/s11095-022-03355-2
By:
- Boosman, René J.;
- Jebbink, Merel;
- Veldhuis, Wouter B.;
- Groenland, Stefanie L.;
- van Veggel, Bianca A. M. H.;
- Moeskops, Pim;
- de Langen, Adrianus J.;
- Beijnen, Jos H.;
- Smit, Egbert F.;
- Huitema, Alwin D. R.;
- Steeghs, Neeltje
Publication type:
Article
Phase I pharmacological study of continuous chronomodulated capecitabine treatment.
Published in:
Pharmaceutical Research, 2020, v. 37, n. 5, p. 1, doi. 10.1007/s11095-020-02828-6
By:
- Roosendaal, Jeroen;
- Jacobs, Bart A. W.;
- Pluim, Dick;
- Rosing, Hilde;
- de Vries, Niels;
- van Werkhoven, Erik;
- Nuijen, Bastiaan;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.;
- Schellens, Jan H. M.;
- Marchetti, Serena
Publication type:
Article
Sialic Acid-Engineered IL4–10 Fusion Protein is Bioactive and Rapidly Cleared from the Circulation.
Published in:
Pharmaceutical Research, 2020, v. 37, n. 2, p. 1, doi. 10.1007/s11095-019-2744-y
By:
- Steen-Louws, Cristine;
- Boross, Peter;
- Prado, Judith;
- Meeldijk, Jan;
- Langenhorst, Jurgen B.;
- Huitema, Alwin D. R.;
- den Hartog, Marcel T.;
- Boon, Louis;
- Lafeber, Floris P. J. G.;
- Hack, C. Erik;
- Eijkelkamp, Niels;
- Popov-Celeketic, Jelena
Publication type:
Article
Does Older Age Lead to Higher Risk for Neutropenia in Patients Treated with Paclitaxel?
Published in:
Pharmaceutical Research, 2019, v. 36, n. 12, p. N.PAG, doi. 10.1007/s11095-019-2697-1
By:
- Crombag, Marie-Rose B. S.;
- Koolen, Stijn L. W.;
- Wijngaard, Sophie;
- Joerger, Markus;
- Dorlo, Thomas P. C.;
- van Erp, Nielka P.;
- Mathijssen, Ron H. J.;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.
Publication type:
Article
Exposure to Docetaxel in the Elderly Patient Population: a Population Pharmacokinetic Study.
Published in:
Pharmaceutical Research, 2019, v. 36, n. 12, p. N.PAG, doi. 10.1007/s11095-019-2706-4
By:
- Crombag, Marie-Rose B. S.;
- Dorlo, Thomas P. C.;
- van der Pan, Ellen;
- van Straten, Anoek;
- Bergman, Andries M.;
- van Erp, Nielka P.;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.
Publication type:
Article
Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study.
Published in:
Pharmaceutical Research, 2019, v. 36, n. 2, p. 1, doi. 10.1007/s11095-018-2563-6
By:
- Crombag, Marie-Rose B. S.;
- de Vries Schultink, Aurelia H. M.;
- Koolen, Stijn L.W.;
- Wijngaard, Sophie;
- Joerger, Markus;
- Schellens, Jan H. M.;
- Dorlo, Thomas P. C.;
- van Erp, Nielka P.;
- Mathijssen, Ron H. J.;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.
Publication type:
Article
A simple extemporaneous oral suspension of aprepitant yields sufficient pharmacokinetic exposure in children.
Published in:
Journal of Oncology Pharmacy Practice, 2023, v. 29, n. 4, p. 899, doi. 10.1177/10781552221089243
By:
- Nijstad, A Laura;
- de Vos-Kerkhof, Evelien;
- Enters-Weijnen, Catherine F;
- van de Wetering, Marianne D;
- Tissing, Wim J E;
- Hanff, Lidwien M;
- Lange, Rogier;
- Tibben, Matthijs M;
- Rosing, Hilde;
- Lalmohamed, Arief;
- Zwaan, C Michel;
- Huitema, Alwin D R
Publication type:
Article
Quantification of the pharmacokinetic-toxicodynamic relationship of oral docetaxel co-administered with ritonavir.
Published in:
Investigational New Drugs, 2020, v. 38, n. 5, p. 1526, doi. 10.1007/s10637-020-00935-0
By:
- Yu, Huixin;
- Janssen, Julie M.;
- de Weger, Vincent A.;
- Nuijen, Bastiaan;
- Stuurman, Rik E.;
- Marchetti, Serena;
- Schellens, Jan H. M.;
- Beijnen, Jos H.;
- Dorlo, Thomas P. C.;
- Huitema, Alwin D. R.
Publication type:
Article
Mass balance and metabolite profiling of 14C-guadecitabine in patients with advanced cancer.
Published in:
Investigational New Drugs, 2020, v. 38, n. 4, p. 1085, doi. 10.1007/s10637-019-00854-9
By:
- Roosendaal, Jeroen;
- Rosing, Hilde;
- Lucas, Luc;
- Gebretensae, Abadi;
- Huitema, Alwin D. R.;
- van Dongen, Marloes G.;
- Beijnen, Jos H.;
- Oganesian, Aram
Publication type:
Article
Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose.
Published in:
Investigational New Drugs, 2018, v. 36, n. 6, p. 1006, doi. 10.1007/s10637-018-0593-x
By:
- de Vries Schultink, Aurelia H. M.;
- Doornbos, Robert P.;
- Bakker, Alexander B. H.;
- Bol, Kees;
- Throsby, Mark;
- Geuijen, Cecile;
- Maussang, David;
- Schellens, Jan H. M.;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.
Publication type:
Article
Concentrations of Erlotinib in Tumor Tissue and Plasma in Non-Small-Cell Lung Cancer Patients After Neoadjuvant Therapy.
Published in:
2015
By:
- Lankheet, Nienke A G;
- Schaake, Eva E;
- Burgers, Sjaak A;
- van Pel, Renée;
- Beijnen, Jos H;
- Huitema, Alwin D R;
- Klomp, Houke;
- NEL study group;
- NEL Study Group
Publication type:
journal article
Concentrations of Erlotinib in Tumor Tissue and Plasma in Non--Small-Cell Lung Cancer Patients After Neoadjuvant Therapy.
Published in:
Clinical Lung Cancer, 2015, v. 16, n. 4, p. 320, doi. 10.1016/j.cllc.2014.12.012
By:
- Lankheet, Nienke A. G.;
- Schaake, Eva E.;
- Burgers, Sjaak A.;
- van Pel, Renée;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.;
- Klomp, Houke
Publication type:
Article
A Review of CYP3A Drug-Drug Interaction Studies: Practical Guidelines for Patients Using Targeted Oral Anticancer Drugs.
Published in:
Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.670862
By:
- Molenaar-Kuijsten, Laura;
- Van Balen, Dorieke E. M.;
- Beijnen, Jos H.;
- Steeghs, Neeltje;
- Huitema, Alwin D. R.
Publication type:
Article
Predicting the effect of different folate doses on [68Ga]Ga-PSMA-11 organ and tumor uptake using physiologically based pharmacokinetic modeling.
Published in:
EJNMMI Research, 2023, v. 13, n. 1, p. 1, doi. 10.1186/s13550-023-01008-y
By:
- Siebinga, Hinke;
- Hendrikx, Jeroen J. M. A.;
- Huitema, Alwin D. R.;
- de Wit-van der Veen, Berlinda J.
Publication type:
Article
A physiologically based pharmacokinetic model for [68Ga]Ga-(HA-)DOTATATE to predict whole-body distribution and tumor sink effects in GEP-NET patients.
Published in:
EJNMMI Research, 2023, v. 13, n. 1, p. 1, doi. 10.1186/s13550-023-00958-7
By:
- Siebinga, Hinke;
- de Wit-van der Veen, Berlinda J.;
- Beijnen, Jos H.;
- Dorlo, Thomas P. C.;
- Huitema, Alwin D. R.;
- Hendrikx, Jeroen J. M. A.
Publication type:
Article
Optimized Dosing: The Next Step in Precision Medicine in Non-Small-Cell Lung Cancer.
Published in:
Drugs, 2022, v. 82, n. 1, p. 15, doi. 10.1007/s40265-021-01654-3
By:
- Boosman, René J.;
- Burgers, Jacobus A.;
- Smit, Egbert F.;
- Steeghs, Neeltje;
- van der Wekken, Anthonie J.;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.;
- ter Heine, Rob
Publication type:
Article
Population Pharmacokinetics of Intracellular 5-Fluorouridine 5′-Triphosphate and its Relationship with Hand-and-Foot Syndrome in Patients Treated with Capecitabine.
Published in:
AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00533-1
By:
- Janssen, Julie M.;
- Jacobs, Bart A. W.;
- Roosendaal, Jeroen;
- Derissen, Ellen J. B.;
- Marchetti, Serena;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.;
- Dorlo, Thomas P. C.
Publication type:
Article
Quantification of T Cell Binding Polyclonal Rabbit Anti-thymocyte Globulin in Human Plasma with Liquid Chromatography Tandem-Mass Spectrometry.
Published in:
AAPS Journal, 2020, v. 22, n. 2, p. 1, doi. 10.1208/s12248-020-0419-6
By:
- Amrani, Mohsin El;
- Admiraal, Rick;
- Willaert, Lobke;
- Ebskamp-van Raaij, Lysette J. C.;
- Lacna, Amelia M.;
- Hack, C. Erik;
- Huitema, Alwin D. R.;
- Nierkens, Stefan;
- van Maarseveen, Erik M.
Publication type:
Article
Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N',N"-triethylenethiophosphoramide (thiotepa) and N,N',N"-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry
Published in:
Journal of Mass Spectrometry, 2004, v. 39, n. 3, p. 262
By:
- Milly E. de Jonge;
- Selma M. van Dam;
- Michel J. X. Hillebrand;
- Hilde Rosing;
- Alwin D. R. Huitema;
- Sjoerd Rodenhuis
Publication type:
Article
Failure of Miltefosine in Visceral Leishmaniasis Is Associated With Low Drug Exposure.
Published in:
2014
By:
- Dorlo, Thomas P. C.;
- Rijal, Suman;
- Ostyn, Bart;
- de Vries, Peter J.;
- Singh, Rupa;
- Bhattarai, Narayan;
- Uranw, Surendra;
- Dujardin, Jean-Claude;
- Boelaert, Marleen;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.
Publication type:
Journal Article
Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin.
Published in:
Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 2, p. 132, doi. 10.1067/mcp.2001.117283
By:
- Kerbusch, Thomas;
- Jansen, Rob L. H.;
- Mathôt, Ron A. A.;
- Huitema, Alwin D. R.;
- Jansen, Myra;
- van Rijswijk, Ruud E. N.;
- Beijnen, Jos H.
Publication type:
Article
Validation of techniques for the prediction of carboplatin exposure: Application of Bayesian methods*.
Published in:
Clinical Pharmacology & Therapeutics, 2000, v. 67, n. 6, p. 621, doi. 10.1067/mcp.2000.106827
By:
- Huitema, Alwin D. R.;
- Mathôt, Ron A. A.;
- Tibben, Matthijs M.;
- Schellens, Jan H. M.;
- Rodenhuis, Sjoerd;
- Beijnen, Jos H.
Publication type:
Article
Image-based analysis of skeletal muscle mass predicts cisplatin dose-limiting toxicity in patients with locally advanced head and neck cancer.
Published in:
European Archives of Oto-Rhino-Laryngology, 2022, v. 279, n. 7, p. 3685, doi. 10.1007/s00405-021-07229-y
By:
- Chargi, Najiba;
- Bashiri, Fereshta;
- Wendrich, Anne W.;
- Smid, Ernst J.;
- de Jong, Pim A.;
- Huitema, Alwin D. R.;
- Devriese, Lot. A.;
- de Bree, Remco
Publication type:
Article
A joint model of longitudinal pharmacokinetic and time-to-event data to study exposure–response relationships: a proof-of-concept study with alectinib.
Published in:
Cancer Chemotherapy & Pharmacology, 2024, v. 94, n. 3, p. 453, doi. 10.1007/s00280-024-04698-w
By:
- Lin, Lishi;
- van der Noort, Vincent;
- Steeghs, Neeltje;
- Ruiter, Gerrina;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.
Publication type:
Article
Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data.
Published in:
Cancer Chemotherapy & Pharmacology, 2024, v. 94, n. 1, p. 25, doi. 10.1007/s00280-024-04640-0
By:
- Lau, Cedric;
- Mohmaed Ali, Ma Ida;
- Lin, Lishi;
- van Balen, Dorieke E. M.;
- Jacobs, Bart A. W.;
- Nuijen, Bastiaan;
- Smeenk, Robert M.;
- Steeghs, Neeltje;
- Huitema, Alwin D. R.
Publication type:
Article
Predicting [177Lu]Lu-HA-DOTATATE kidney and tumor accumulation based on [68Ga]Ga-HA-DOTATATE diagnostic imaging using semi-physiological population pharmacokinetic modeling.
Published in:
EJNMMI Physics, 2023, v. 10, n. 1, p. 1, doi. 10.1186/s40658-023-00565-4
By:
- Siebinga, Hinke;
- de Wit-van der Veen, Berlinda J.;
- Beijnen, Jos H.;
- Stokkel, Marcel P. M.;
- Dorlo, Thomas P. C.;
- Huitema, Alwin D. R.;
- Hendrikx, Jeroen J. M. A.
Publication type:
Article
Optimizing carboplatin dosing by an improved prediction of carboplatin clearance using a CT‐enhanced estimate of renal function.
Published in:
British Journal of Clinical Pharmacology, 2023, v. 89, n. 10, p. 3016, doi. 10.1111/bcp.15789
By:
- Molenaar‐Kuijsten, Laura;
- Pieters, Tobias T.;
- Veldhuis, Wouter B.;
- Moeskops, Pim;
- Rijkhorst, Erik Jan;
- Dorlo, Thomas P. C.;
- Beijnen, Jos H.;
- Steeghs, Neeltje;
- Rookmaaker, Maarten B.;
- Huitema, Alwin D. R.
Publication type:
Article
Prediction of the pharmacokinetics of pemetrexed with a low test dose: A proof‐of‐concept study.
Published in:
British Journal of Clinical Pharmacology, 2023, v. 89, n. 2, p. 699, doi. 10.1111/bcp.15520
By:
- Boosman, René J.;
- de Rouw, Nikki;
- Huitema, Alwin D. R.;
- Burgers, Jacobus A.;
- ter Heine, Rob
Publication type:
Article
Hyperhydration with cisplatin does not influence pemetrexed exposure.
Published in:
British Journal of Clinical Pharmacology, 2022, v. 88, n. 2, p. 871, doi. 10.1111/bcp.15031
By:
- de Rouw, Nikki;
- Derijks, Hieronymus J.;
- Hilbrands, Luuk B.;
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- Koolen, Stijn L. W.;
- Burgers, Jacobus A.;
- Dingemans, Anne‐Marie C.;
- van den Heuvel, Michel M.;
- Hendriks, Lizza E. L.;
- Aerts, Joachim G. J. V.;
- Croes, Sander;
- Mathijssen, Ron H. J.;
- Huitema, Alwin D. R.;
- Burger, David M.;
- Biesma, Bonne;
- ter Heine, Rob
Publication type:
Article
A semi‐mechanistic model based on glutathione depletion to describe intra‐individual reduction in busulfan clearance.
Published in:
British Journal of Clinical Pharmacology, 2020, v. 86, n. 8, p. 1499, doi. 10.1111/bcp.14256
By:
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- Boss, Jill;
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- Kuball, Jürgen;
- Egberts, Antoine C. G.;
- Boelens, Jaap Jan;
- Huitema, Alwin D. R.;
- Maarseveen, Erik M.
Publication type:
Article
Food‐effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.
Published in:
British Journal of Clinical Pharmacology, 2018, v. 84, n. 12, p. 2761, doi. 10.1111/bcp.13719
By:
- Henricks, Linda M.;
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- Beijnen, Jos H.;
- Huitema, Alwin D. R.;
- Guchelaar, Henk‐Jan;
- Cats, Annemieke;
- Schellens, Jan H. M.
Publication type:
Article

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