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In vitro and in vivo consequences of variant medium-chain acyl-CoA dehydrogenase genotypes.
Published in:
Orphanet Journal of Rare Diseases, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1172-8-43
By:
- Touw, Catharina ML;
- Smit, G Peter A.;
- Niezen-Koning, Klary E.;
- Boer, Conny Bosgraaf-de;
- Gerding, Albert;
- Reijngoud, Dirk-Jan;
- Derks, Terry GJ
Publication type:
Article
In vitro and in vivo consequences of variant medium-chain acyl-CoA dehydrogenase genotypes.
Published in:
2013
By:
- Touw, Catharina Ml;
- Smit, G Peter A;
- Niezen-Koning, Klary E;
- Boer, Conny Bosgraaf-de;
- Gerding, Albert;
- Reijngoud, Dirk-Jan;
- Derks, Terry Gj;
- Touw, Catharina M L;
- Bosgraaf-de Boer, Conny;
- Derks, Terry G J
Publication type:
journal article
Selective Hepatic Cbs Knockout Aggravates Liver Damage, Endothelial Dysfunction and ROS Stress in Mice Fed a Western Diet.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 8, p. 7019, doi. 10.3390/ijms24087019
By:
- Lambooy, Sebastiaan;
- Heida, Andries;
- Joschko, Christian;
- Nakladal, Dalibor;
- van Buiten, Azuwerus;
- Kloosterhuis, Niels;
- Huijkman, Nicolette;
- Gerding, Albert;
- van de Sluis, Bart;
- Henning, Robert;
- Deelman, Leo
Publication type:
Article
Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29639-0
By:
- Erdem, Ayşegül;
- Marin, Silvia;
- Pereira-Martins, Diego A.;
- Geugien, Marjan;
- Cunningham, Alan;
- Pruis, Maurien G.;
- Weinhäuser, Isabel;
- Gerding, Albert;
- Bakker, Barbara M.;
- Wierenga, Albertus T. J.;
- Rego, Eduardo M.;
- Huls, Gerwin;
- Cascante, Marta;
- Schuringa, Jan Jacob
Publication type:
Article
Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload.
Published in:
BMC Biology, 2021, v. 19, n. 1, p. 1, doi. 10.1186/s12915-021-01082-5
By:
- Vieira-Lara, Marcel A.;
- Dommerholt, Marleen B.;
- Zhang, Wenxuan;
- Blankestijn, Maaike;
- Wolters, Justina C.;
- Abegaz, Fentaw;
- Gerding, Albert;
- van der Veen, Ydwine T.;
- Thomas, Rachel;
- van Os, Ronald P.;
- Reijngoud, Dirk-Jan;
- Jonker, Johan W.;
- Kruit, Janine K.;
- Bakker, Barbara M.
Publication type:
Article
Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload.
Published in:
BMC Biology, 2021, v. 19, n. 1, p. 1, doi. 10.1186/s12915-021-01082-5
By:
- Vieira-Lara, Marcel A.;
- Dommerholt, Marleen B.;
- Wenxuan Zhang;
- Blankestijn, Maaike;
- Wolters, Justina C.;
- Abegaz, Fentaw;
- Gerding, Albert;
- van der Veen, Ydwine T.;
- Thomas, Rachel;
- van Os, Ronald P.;
- Reijngoud, Dirk-Jan;
- Jonker, Johan W.;
- Kruit, Janine K.;
- Bakker, Barbara M.
Publication type:
Article
Targeting pathogen metabolism without collateral damage to the host.
Published in:
Scientific Reports, 2017, p. 40406, doi. 10.1038/srep40406
By:
- Haanstra, Jurgen R.;
- Gerding, Albert;
- Dolga, Amalia M.;
- Sorgdrager, Freek J. H.;
- Buist-Homan, Manon;
- du Toit, François;
- Faber, Klaas Nico;
- Holzhütter, Hermann-Georg;
- Szöör, Balázs;
- Matthews, Keith R.;
- Snoep, Jacky L.;
- Westerhoff, Hans V.;
- Bakker, Barbara M.
Publication type:
Article
Protection against the Metabolic Syndrome by Guar Gum-Derived Short-Chain Fatty Acids Depends on Peroxisome Proliferator-Activated Receptor γ and Glucagon-Like Peptide-1.
Published in:
PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0136364
By:
- den Besten, Gijs;
- Gerding, Albert;
- van Dijk, Theo H.;
- Ciapaite, Jolita;
- Bleeker, Aycha;
- van Eunen, Karen;
- Havinga, Rick;
- Groen, Albert K.;
- Reijngoud, Dirk-Jan;
- Bakker, Barbara M.
Publication type:
Article
The Short-Chain Fatty Acid Uptake Fluxes by Mice on a Guar Gum Supplemented Diet Associate with Amelioration of Major Biomarkers of the Metabolic Syndrome.
Published in:
PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107392
By:
- den Besten, Gijs;
- Havinga, Rick;
- Bleeker, Aycha;
- Rao, Shodhan;
- Gerding, Albert;
- van Eunen, Karen;
- Groen, Albert K.;
- Reijngoud, Dirk-Jan;
- Bakker, Barbara M.
Publication type:
Article
Bile Acid Sequestration Reduces Plasma Glucose Levels in db/db Mice by Increasing Its Metabolic Clearance Rate.
Published in:
PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0024564
By:
- Meissner, Maxi;
- Herrema, Hilde;
- Dijk, Theo H. van;
- Gerding, Albert;
- Havinga, Rick;
- Boer, Theo;
- Müller, Michael;
- Reijngoud, Dirk-Jan.;
- Groen, Albert K.;
- Kuipers, Folkert
Publication type:
Article
Short‐term protein restriction at advanced age stimulates FGF21 signalling, energy expenditure and browning of white adipose tissue.
Published in:
FEBS Journal, 2021, v. 288, n. 7, p. 2257, doi. 10.1111/febs.15604
By:
- Dommerholt, Marleen B.;
- Blankestijn, Maaike;
- Vieira‐Lara, Marcel A.;
- van Dijk, Theo H.;
- Wolters, Henk;
- Koster, Mirjam H.;
- Gerding, Albert;
- van Os, Ronald P.;
- Bloks, Vincent W.;
- Bakker, Barbara M.;
- Kruit, Janine K.;
- Jonker, Johan W.
Publication type:
Article
Fibroblast‐specific genome‐scale modelling predicts an imbalance in amino acid metabolism in Refsum disease.
Published in:
FEBS Journal, 2020, v. 287, n. 23, p. 5096, doi. 10.1111/febs.15292
By:
- Wegrzyn, Agnieszka B.;
- Herzog, Katharina;
- Gerding, Albert;
- Kwiatkowski, Marcel;
- Wolters, Justina C.;
- Dolga, Amalia M.;
- Lint, Alida E. M.;
- Wanders, Ronald J. A.;
- Waterham, Hans R.;
- Bakker, Barbara M.
Publication type:
Article
Transcriptome analysis suggests a compensatory role of the cofactors coenzyme A and NAD<sup>+</sup> in medium-chain acyl-CoA dehydrogenase knockout mice.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-50758-0
By:
- Martines, Anne-Claire M. F.;
- Gerding, Albert;
- Stolle, Sarah;
- Vieira-Lara, Marcel A.;
- Wolters, Justina C.;
- Jurdzinski, Angelika;
- Bongiovanni, Laura;
- de Bruin, Alain;
- van der Vlies, Pieter;
- van der Vries, Gerben;
- Bloks, Vincent W.;
- Derks, Terry G. J.;
- Reijngoud, Dirk-Jan;
- Bakker, Barbara M.
Publication type:
Article
Spontaneous liver disease in wild-type C57BL/6JOlaHsd mice fed semisynthetic diet.
Published in:
PLoS ONE, 2020, v. 15, n. 9, p. 1, doi. 10.1371/journal.pone.0232069
By:
- Ronda, Onne A. H. O.;
- van de Heijning, Bert J. M.;
- de Bruin, Alain;
- Thomas, Rachel E.;
- Martini, Ingrid;
- Koehorst, Martijn;
- Gerding, Albert;
- Koster, Mirjam H.;
- Bloks, Vincent W.;
- Jurdzinski, Angelika;
- Mulder, Niels L.;
- Havinga, Rick;
- van der Beek, Eline M.;
- Reijngoud, Dirk-Jan;
- Kuipers, Folkert;
- Verkade, Henkjan J.
Publication type:
Article
Biochemical Competition Makes Fatty-Acid β-Oxidation Vulnerable to Substrate Overload.
Published in:
PLoS Computational Biology, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.pcbi.1003186
By:
- van Eunen, Karen;
- Simons, Sereh M. J.;
- Gerding, Albert;
- Bleeker, Aycha;
- den Besten, Gijs;
- Touw, Catharina M. L.;
- Houten, Sander M.;
- Groen, Bert K.;
- Krab, Klaas;
- Reijngoud, Dirk-Jan;
- Bakker, Barbara M.
Publication type:
Article
Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders.
Published in:
BMC Biology, 2016, v. 14, p. 1, doi. 10.1186/s12915-016-0327-5
By:
- van Eunen, Karen;
- Volker-Touw, Catharina M. L.;
- Gerding, Albert;
- Bleeker, Aycha;
- Wolters, Justina C.;
- van Rijt, Willemijn J.;
- Martines, Anne-Claire M. F.;
- Niezen-Koning, Klary E.;
- Heiner, Rebecca M.;
- Permentier, Hjalmar;
- Groen, Albert K.;
- Reijngoud, Dirk-Jan;
- Derks, Terry G. J.;
- Bakker, Barbara M.
Publication type:
Article
Impaired Very‐Low‐Density Lipoprotein catabolism links hypoglycemia to hypertriglyceridemia in Glycogen Storage Disease type Ia.
Published in:
Journal of Inherited Metabolic Disease, 2021, v. 44, n. 4, p. 879, doi. 10.1002/jimd.12380
By:
- Hoogerland, Joanne A.;
- Peeks, Fabian;
- Hijmans, Brenda S.;
- Wolters, Justina C.;
- Kooijman, Sander;
- Bos, Trijnie;
- Bleeker, Aycha;
- Dijk, Theo H.;
- Wolters, Henk;
- Gerding, Albert;
- Eunen, Karen;
- Havinga, Rick;
- Pronk, Amanda C. M.;
- Rensen, Patrick C. N.;
- Mithieux, Gilles;
- Rajas, Fabienne;
- Kuipers, Folkert;
- Reijngoud, Dirk‐Jan;
- Derks, Terry G. J.;
- Oosterveer, Maaike H.
Publication type:
Article
A toolbox for the comprehensive analysis of small volume human intestinal samples that can be used with gastrointestinal sampling capsules.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-86980-y
By:
- Rios-Morales, Melany;
- van Trijp, Mara P. H.;
- Rösch, Christiane;
- An, Ran;
- Boer, Theo;
- Gerding, Albert;
- de Ruiter, Naomi;
- Koehorst, Martijn;
- Heiner-Fokkema, M. Rebecca;
- Schols, Henk A.;
- Reijngoud, Dirk-Jan;
- Hooiveld, Guido J. E. J.;
- Bakker, Barbara M.
Publication type:
Article
Effects of lysine deacetylase inhibitor treatment on LPS responses of alveolar-like macrophages.
Published in:
Journal of Leukocyte Biology, 2024, v. 115, n. 3, p. 435, doi. 10.1093/jleuko/qiad121
By:
- Russo, Sara;
- Kwiatkowski, Marcel;
- Wolters, Justina C;
- Gerding, Albert;
- Hermans, Jos;
- Govorukhina, Natalia;
- Bischoff, Rainer;
- Melgert, Barbro N
Publication type:
Article
Acute Inhibition of Medium-Chain Fatty Acid Oxidation In Vivo Only Slightly Inhibits Endogenous Glucose Production in Short Term Fasted Male C57BL/6J Mice.
Published in:
Diabetes, 2007, v. 56, p. A391
By:
- Reijngoud, Dirk-Jan;
- Derks, Terry G.;
- Van Dijk, Theo H.;
- Gerding, Albert;
- Van Der Sluijs, Fjodor H.;
- Smit, G. Peter A.;
- Havinga, Rick;
- Kuipers, Folkert
Publication type:
Article
Personalised modelling of clinical heterogeneity between medium-chain acyl-CoA dehydrogenase patients.
Published in:
BMC Biology, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12915-023-01652-9
By:
- Odendaal, Christoff;
- Jager, Emmalie A.;
- Martines, Anne-Claire M. F.;
- Vieira-Lara, Marcel A.;
- Huijkman, Nicolette C. A.;
- Kiyuna, Ligia A.;
- Gerding, Albert;
- Wolters, Justina C.;
- Heiner-Fokkema, Rebecca;
- van Eunen, Karen;
- Derks, Terry G. J.;
- Bakker, Barbara M.
Publication type:
Article
A Kinase Interacting Protein 1 regulates mitochondrial protein levels in energy metabolism and promotes mitochondrial turnover after exercise.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-45961-z
By:
- Nijholt, Kirsten T.;
- Sánchez-Aguilera, Pablo I.;
- Mahmoud, Belend;
- Gerding, Albert;
- Wolters, Justina C.;
- Wolters, Anouk H. G.;
- Giepmans, Ben N. G.;
- Silljé, Herman H. W.;
- de Boer, Rudolf A.;
- Bakker, Barbara M.;
- Westenbrink, B. Daan
Publication type:
Article
Heptanoate Improves Compensatory Mechanism of Glucose Homeostasis in Mitochondrial Long-Chain Fatty Acid Oxidation Defect.
Published in:
Nutrients, 2023, v. 15, n. 21, p. 4689, doi. 10.3390/nu15214689
By:
- Nurjanah, Siti;
- Gerding, Albert;
- Vieira-Lara, Marcel A.;
- Evers, Bernard;
- Langelaar-Makkinje, Miriam;
- Spiekerkoetter, Ute;
- Bakker, Barbara M.;
- Tucci, Sara
Publication type:
Article
A Systems Analysis of Phenotype Heterogeneity in APOE*3Leiden.CETP Mice Induced by Long-Term High-Fat High-Cholesterol Diet Feeding.
Published in:
Nutrients, 2022, v. 14, n. 22, p. 4936, doi. 10.3390/nu14224936
By:
- Paalvast, Yared;
- Zhou, Enchen;
- Rozendaal, Yvonne J. W.;
- Wang, Yanan;
- Gerding, Albert;
- van Dijk, Theo H.;
- de Boer, Jan Freark;
- Rensen, Patrick C. N.;
- van Dijk, Ko Willems;
- Kuivenhoven, Jan A.;
- Bakker, Barbara M.;
- van Riel, Natal A. W.;
- Groen, Albert K.
Publication type:
Article
The Effects of Butyrate on Induced Metabolic-Associated Fatty Liver Disease in Precision-Cut Liver Slices.
Published in:
Nutrients, 2021, v. 13, n. 12, p. 4203, doi. 10.3390/nu13124203
By:
- Prins, Grietje H.;
- Rios-Morales, Melany;
- Gerding, Albert;
- Reijngoud, Dirk-Jan;
- Olinga, Peter;
- Bakker, Barbara M.
Publication type:
Article
Short-Chain Fatty Acids Protect Against High-Fat Diet-Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation.
Published in:
2015
By:
- den Besten, Gijs;
- Bleeker, Aycha;
- Gerding, Albert;
- van Eunen, Karen;
- Havinga, Rick;
- van Dijk, Theo H;
- Oosterveer, Maaike H;
- Jonker, Johan W;
- Groen, Albert K;
- Reijngoud, Dirk-Jan;
- Bakker, Barbara M
Publication type:
journal article
Short-Chain Fatty Acids Protect Against High-Fat Diet--Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation.
Published in:
Diabetes, 2015, v. 64, n. 7, p. 2398, doi. 10.2337/db14-1213
By:
- den Besten, Gijs;
- Bleeker, Aycha;
- Gerding, Albert;
- van Eunen, Karen;
- Havinga, Rick;
- van Dijk, Theo H.;
- Oosterveer, Maaike H.;
- Jonker, Johan W.;
- Groen, Albert K.;
- Reijngoud, Dirk-Jan;
- Bakker, Barbara M.
Publication type:
Article
Renal temperature reduction progressively favors mitochondrial ROS production over respiration in hypothermic kidney preservation.
Published in:
2019
By:
- Hendriks, Koen D. W.;
- Brüggenwirth, Isabel M. A.;
- Maassen, Hanno;
- Gerding, Albert;
- Bakker, Barbara;
- Porte, Robert J.;
- Henning, Robert H.;
- Leuvenink, Henri G. D.
Publication type:
journal article

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