We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Survey of severe respiratory syncytial virus infection in Kyoto Prefecture from 2003 to 2007.
- Authors
Ito, Hisato; Osamura, Toshio; Nakajima, Fumiaki; Fujiwara, Daisuke; Kuwabara, Yasumichi; Yamamoto, Toru; Yasuno, Tetsuya; Komatsu, Hiroshi; Kizaki, Zenrou; Kishida, Kenji; Akiyama, Yuichi; Oomae, Tadaki; Nakajima, Kouji; Nakamura, Akitoshi; Kiyosawa, Nobuyuki; Nisikomori, Ryuta
- Abstract
Background: Respiratory syncytial virus (RSV) infection in infants can develop into a severe condition. Methods: A survey of patients with severe RSV infection in hospitals in Kyoto Prefecture was performed from 2003 to 2007. Patients requiring intubation and those with cardiopulmonary arrest on arrival (CPAOA) were considered to have severe RSV infection. Results: Twenty-five patients with severe infection were identified and detailed data were available for 21 patients, of whom 18 required intubation and three had CPAOA. The male/female ratio was 12/9 and age ranged from 8 days to 19 years (average, 5.2 months; median: 2 months). At admission white blood cell count, lactate dehydrogenase ( P < 0.05), and blood glucose ( P < 0.01) were higher and Na was lower ( P < 0.01) in the 18 patients with severe infection (excluding the CPAOA cases) compared to 18 sex- and age-matched patients with mild RSV infection. The incidence of bacterial infection was also higher in severe cases ( P < 0.05). The outcome was death in four patients (19.0%, including two sudden deaths), aftereffects in two (9.5%), hospital discharge with improvement in 14 (66.7%), and an unclear outcome in one patient. Excluding the two sudden death cases, 14 of 19 patients (73.7%) were extubated within 2 weeks. The period of intubation was longer in older patients ( P < 0.05). Conclusion: Because severe RSV infection led to sudden death in two cases, detection of RSV is important at admission for an infant with CPAOA. Fourteen patients (66.7%), however, had good outcomes and most patients were extubated within 2 weeks.
- Subjects
KYOTO (Japan); JAPAN; CARDIAC arrest in children; COMPLICATIONS of viral diseases in children; INTUBATION; SUDDEN death in children; HEALTH outcome assessment
- Publication
Pediatrics International, 2010, Vol 52, Issue 2, p273
- ISSN
1328-8067
- Publication type
Article
- DOI
10.1111/j.1442-200X.2009.02962.x