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- Title
PERSPECTIVES ON THE USE OF LIPID NANOCARRIERS IN THE TOPICAL TREATMENT OF PSORIASIS.
- Authors
Ochiuz, Lăcrămioara; Ştefanache, Alina; Ghiciuc, Cristina
- Abstract
Psoriasis is an inflammatory, autoimmune dermatosis with multifactorial etiology and chronic evolution with major repercussions on the patient's quality of life (QoL). The therapeutic management of psoriasis depends on the severity of the disease. Conventionally, the topical therapy indicated for patients with psoriasis includes corticosteroids, vitamin D analogues, retinoids, calcineurin inhibitors, anthralin and tar. Although the topical medication of this condition shows several numbers of advantages, mentioning the reduced risk of side effects and treatment compliance, however, the disadvantages of this therapy should also to be highlighted, the most important being the fluctuating bioavailability determined by the skin barrier function. Development of nano pharmaceutical formulations in close correlation with the influence of nanotechnology in pharmaceutical research opens new perspectives in optimizing topical medication of psoriasis. Currently, several clinical studies with topical nanoformulations are underway to optimize the therapeutic management of psoriasis.
- Subjects
NANOCARRIERS; PSORIASIS; PATIENT compliance; VITAMIN D; TREATMENT effectiveness
- Publication
International Journal of Medical Dentistry, 2020, Vol 24, Issue 2, p309
- ISSN
2066-6063
- Publication type
Article