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- Title
Frequency of Low Immunglobuline level in Pre-School Recurrent Wheezing.
- Authors
YOLDAŞ ÇELİK, Merve; KÜLHAŞ ÇELİK, İlknur; GİNİŞ, Tayfur; BÜYÜKTİRYAKİ, Betül; TOYRAN, Müge; DİBEK MISIRLIOĞLU, Emine; KOCABAŞ, Can Naci; CİVELEK, Ersoy
- Abstract
Objective: Immunoglobulin lowering may be associated with recurrent wheezing symptoms and clinic by increasing the tendency to viral respiratory tract infections. This study aimed to investigate the frequency of immunoglobulinemia in preschoolers with wheezing. Material and Methods: The study was conducted between 01.01.2013 - 01.01.2016 between T.C. University of Health Sciences, Ankara Child Health and Diseases Hematology Oncology Training, and Research Hospital, The Pediatric Allergy and Immunology Clinic included patients who had been followed up and treated for at least one year with recurrent wheezing attacks within 72 months. The patients' immunoglobulin (G, A, M) values were retrospectively analyzed. Immunoglobulin levels were determined to be normal and low according to age limits. Results: The study included 585 patients (65.6% male, 34.4% female) under the age of 6 years with a mean age of 26.9 months. The mean follow-up period of the patients is 2.2 years. In 33.7% of these patients, at least one immunoglobulin was low. None of these patients had any signs or symptoms of immunodeficiency. Immunoglobulin A was low in 21% of the patients, immünglobulin G in 18%, and immünglobulin M in 7.5% of all patients. Conclusion: Hypogammaglobulinemia was found in approximately 1/3 of the patients. There were no signs of immunodeficiency in these patients. Whether this is a special group in preschooler recurrent wheezing and hypogammaglobulinemia combination should be etiologically investigated.
- Subjects
IMMUNOGLOBULINS; WHEEZE; AGAMMAGLOBULINEMIA
- Publication
Journal of Pediatric Disease / Türkiye Çocuk Hastalıkları Dergisi, 2023, Vol 17, Issue 6, p1
- ISSN
1307-4490
- Publication type
Article
- DOI
10.12956/tchd.1268678