We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Clinical implication and management of rectal cancer with clinically suspicious lateral pelvic lymph node metastasis: A radiation oncologist's perspective.
- Authors
Gyu Sang Yoo; Hee Chul Park; Jeong Il Yu
- Abstract
Rectal cancer is the eighth most common malignancy worldwide. With the introduction of total mesorectal excision (TME) and neoadjuvant chemoradiation (NCRT), intrapelvic local control has been remarkably improved. However, lateral pelvic recurrence remains problematic, especially in patients with clinically suspicious lateral pelvic lymph node (LPLN). LPLN dissection has been applied for the management of LPLN metastasis, mainly in Japan and other Eastern countries, while the role of NCRT is more emphasized and LPLN dissection is performed in very limited cases in Western countries. However, the optimal management strategy for patients with rectal cancer with suspicious LPLN metastasis has not been determined. Herein, we review the latest studies on the optimal management of LPLN metastasis to suggest the most appropriate treatment policies according to current evidence and discuss future research directions.
- Subjects
JAPAN; LYMPHATIC metastasis; RECTAL cancer; ONCOLOGISTS; WESTERN countries; LYMPH nodes; CANCER patients
- Publication
Frontiers in Oncology, 2022, Vol 12, p01
- ISSN
2234-943X
- Publication type
Article
- DOI
10.3389/fonc.2022.960527