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- Title
Paliperidone extended release for the treatment of pediatric and adolescent patients with Tourette's disorder.
- Authors
Kazuhiko Yamamuro; Manabu Makinodan; Toyosaku Ota; Junzo Iida; Toshifumi Kishimoto
- Abstract
Objective A subgroup of patients with Tourette's disorder (TD) has symptoms refractory to haloperidol, a standard therapeutic drug for TD. Methods We report on three cases of pediatric and adolescent patients who were treated with paliperidone extended release. Results In two cases, TD symptoms were remarkably improved by switching from haloperidol to paliperidone extended release, and in another case, paliperidone extended release showed significant efficacy in treating TD symptoms as the first-line drug. In all cases, no significant adverse side effects were detected. Conclusion Paliperidone extended release may be a strong candidate for the treatment of pediatric and adolescent patients with TD.
- Subjects
ANTIPSYCHOTIC agents; BRAIN; TIC disorders; TOURETTE syndrome; HALOPERIDOL; SYMPTOMS; CHILDREN
- Publication
Annals of General Psychiatry, 2014, Vol 13, Issue 1, p2
- ISSN
1744-859X
- Publication type
Article
- DOI
10.1186/1744-859X-13-13