We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
IL-17 and IL-22 serum levels in greenhouse workers exposed to pesticides.
- Authors
Fenga, Concettina; Gangemi, Silvia; Catania, Stefania; De Luca, Annamaria; Costa, Chiara
- Abstract
Introduction: Altered immune function may be an indicator of increased potential for the development of immunologically based diseases such as cancer, hypersensitivity and autoimmunity. Materials and methods: To investigate whether Th17 and Th22 cells are targeted by pesticide exposure, we analyzed IL-17 and IL-22 serum levels in a population of 64 greenhouse workers. Results and conclusion: A significant increase in IL-22 concentration was observed in serum of the exposed subjects compared to controls. These findings support the hypothesis that exposure to pesticides may reduce host defenses against infections and cancer.
- Subjects
IMMUNOLOGIC diseases; CANCER immunology; ALLERGIES; AUTOIMMUNITY; PESTICIDES; SERUM; HYPOTHESIS
- Publication
Inflammation Research, 2014, Vol 63, Issue 11, p895
- ISSN
1023-3830
- Publication type
Article
- DOI
10.1007/s00011-014-0769-6