We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Short-term efficacy of radiofrequency hyperthermia combined with chemotherapy in treatment of malignant pleural effusion caused by breast cancer.
- Authors
Luo Pengfei; Tang Zhaohui; Huang Honglin
- Abstract
Objective To assess short-term effect of radiofrequency hyperthermia combined with chemotherapy in treatment of pleural effusion caused by breast cancer. Methods Sixty-five patients with malignant pleural effusion caused by breast cancer in this hospital from October 2006 to October 2013 were divided into the treatment group (35 cases) and the control group $30 cases) . The control group was given 40 mg cisplatin and 10 mg dexamethasone while the treatment group added with radiofrequency hyperthermia based on the control group. The two groups were given systemic chemotherapy while the patients' general state of health was improved. Results The complete remission rate (CR) of malignant pleura effusion was 51.4%(18/35) with the response rate (RR) accounting for 91.4% (32/35) in the treatment group while the rates of CR and RR of the control group were 26.7% (8/30) and 70.0% (21/30), respectively. There were statistically significant difference between the two groups (P<0.05). The improvement of quality life were better in the treatment group than those in the control group. The difference was statistically significant (P<0.05). There was no statistical significance in prevalence of toxic reaction between the two groups (P>0.05). Conclusion Radiofrequency hyperthermia combined with chemotherapy was effective in treatment of malignant pleura effusion and significantly improves the quality of life of the patients without increasing the toxicity of chemotherapy.
- Publication
Journal of Modern Medicine & Health, 2015, Vol 31, Issue 6, p810
- ISSN
1009-5519
- Publication type
Article
- DOI
10.3969/j.issn.1009-5519.2015.06.004