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- Title
The Frank-Starling mechanism is not enough: blood volume expansion prominently decreases pulmonary O<sub>2</sub> uptake.
- Authors
Guo, Mei-Han; Diaz-Canestro, Candela; Montero, David
- Abstract
This article discusses a study that aimed to determine whether moderate blood volume expansion (BVexp) can increase cardiac capacity and aerobic capacity in both men and women. The study found that BVexp resulted in increased resting heart rate and left ventricular cardiac output in both sexes. However, it also led to a decrease in pulmonary oxygen uptake during exercise, indicating that expanding blood volume alone may not lead to functional improvements in aerobic capacity. The study suggests that additional adaptations to endurance training and/or hypervolemia may be necessary for enhancing circulatory and aerobic capacities.
- Subjects
BLOOD volume; AEROBIC capacity; VASCULAR resistance; BODY composition; CARDIOVASCULAR system
- Publication
Military Medical Research, 2024, Vol 11, p1
- ISSN
2095-7467
- Publication type
Letter
- DOI
10.1186/s40779-024-00546-3