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- Title
Successful recovery of aplastic anemia following orthotopic liver transplantation for non-A-E acute liver failure.
- Authors
Rajwal, S. R.; Davison, S. M.; Stringer, M. D.; Kinsey, S. E.; McClean, P.
- Abstract
Rajwal SR, Davison SM, Stringer MD, Kinsey SE, McClean P. Successful recovery of aplastic anemia following orthotopic liver transplantation for non-A-E acute liver failure. Pediatr Transplantation 2005: 9: 537–540. © 2005 Blackwell Munksgaard This report describes a teenager who developed aplastic anemia (AA) because of non-A-E acute liver failure (ALF) requiring orthotopic liver transplantation (OLT). His AA did not recover spontaneously and he required treatment with ATG 9 months post-OLT. Bone marrow recovery occurred 4 months after immunotherapy and coincided with further intensification of immunusuppression required to treat early chronic rejection of the liver graft. Three years post-OLT he remains well with good bone marrow and liver function. Intensification of immunosuppression can lead to successful resolution of AA associated with non-A-E ALF.
- Subjects
LIVER failure; TRANSPLANTATION of organs, tissues, etc. in children; APLASTIC anemia; BONE marrow; IMMUNOSUPPRESSION; MEDICAL care for teenagers
- Publication
Pediatric Transplantation, 2005, Vol 9, Issue 4, p537
- ISSN
1397-3142
- Publication type
Article
- DOI
10.1111/j.1399-3046.2005.00321.x