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- Title
Diagnosis of renovascular disease by intra- and extrarenal Doppler scanning.
- Authors
Krumme, Bernd; Blum, Ulrich; Schwertfeger, Eckhard; Flügel, Peter; Höllstin, Frank; Schollmeyer, Peter; Rump, Lars Christian
- Abstract
The purpose of this prospective, angiographically controlled study was to determine the diagnostic value of color Doppler sonography with two differing approaches of scanning in patients with clinical clues for renal artery stenosis (RAS). In 135 hypertensive patients peak systolic velocity in the main renal arteries and the resistive index (RI) of the intrarenal arteries were measured. The RI side-to-side-difference (ΔRI) greater than 0.05 or peak systolic velocity greater than 2 m/s were used to discriminate normal from stenotic renal arteries, defined as angiographically confirmed RAS > 50%. In 88 of 135 patients 107 RAS were demonstrated by selective arteriography. Five renal artery occlusions occurred, which were all diagnosed by color Doppler sonography. Seventysix RAS were detected by increased peak systolic velocity, and an additional 19 stenoses were identified by ARI. The combined analysis of peak systolic velocity and ARI resulted in a sensitivity of 89% and specificity of 92%. The positive predictive value was 92% and the negative predictive value was 88%. Our data suggest that only the combination of intra- and extrarenal scanning with color Doppler sonography represents an effective screening method for significant renal artery stenosis in hypertensive patients.
- Subjects
RENOVASCULAR hypertension; DOPPLER ultrasonography; ARTERIAL stenosis; RENAL hypertension; KIDNEY disease diagnosis; KIDNEY diseases
- Publication
Kidney International, 1996, Vol 50, Issue 4, p1288
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1038/ki.1996.440