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- Title
Combination of ABO blood group incompatibility and glucose-6-phosphate dehydrogenase deficiency: effect on hemolysis and neonatal hyperbilirubinemia.
- Authors
Kaplan, M; Vreman, HJ; Hammerman, C; Leiter, C; Rudensky, B; MacDonald, MG; Stevenson, DK; Vreman, H J; MacDonald, M G; Stevenson, D K
- Abstract
The incidence (%) of hyperbilirubinemia (serum bilirubin > or = 257 micromol/l) was similar in neonates with a combination of ABO incompatibility and glucose-6-phosphate dehydrogenase (G-6-PD) deficiency (45%), with ABO incompatibility (54%) or G-6-PD deficiency (37%), alone (ns). Carboxyhemoglobin values, corrected for inspired CO, were similarly elevated in all three groups (0.87 +/- 0.32%, 0.82 +/- 0.29%, 0.76 +/- 0.18%, respectively, ns), but correlated with bilirubin only in those with ABO incompatibility alone. ABO-incompatible/G-6-PD-deficient neonates, compared with those with either condition alone, are not at increased risk for hemolysis or hyperbilirubinemia.
- Subjects
HYPERBILIRUBINEMIA; ABO blood group system; GLUCOSE-6-phosphate dehydrogenase; HEMOLYSIS &; hemolysins; THERAPEUTICS; COMPARATIVE studies; NEONATAL jaundice; RESEARCH methodology; MEDICAL cooperation; INBORN errors of metabolism; RESEARCH; EVALUATION research; CARBOXYHEMOGLOBIN; BLOOD group incompatibility; DISEASE complications
- Publication
Acta Paediatrica, 1998, Vol 87, Issue 4, p455
- ISSN
0803-5253
- Publication type
journal article
- DOI
10.1111/j.1651-2227.1998.tb01478.x