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- Title
Study of neuromyopathy in amyloid kidney transplant patients.
- Authors
Sobh, Mohamed; Refaie, Ayman; El-Tantawy, Abd El-Halim; Saad, Mohamed; Said, Ehab; Arif, Shaker; El-Sherif, Assem; Ghoneim, Mohamed; Sobh, M; Refaie, A; El-Tantawy, A E; Saad, M; Said, E; Arif, S; El-Sherif, A; Ghoneim, M
- Abstract
Neuromuscular status of amyloid and control groups of kidney transplant recipients was assessed through complete neurological examination, assay for serum levels of muscle enzymes (CPK and LDH), electromyography and nerve conduction velocity studies. Neuromyopathic findings were detected in both groups but without severe disabling clinical manifestations. These findings were more prominent in the amyloid group, evidenced by a more significant increase in polyphasicity detected by electromyography and longer prolongation of terminal latency measured in the median nerve. From this study, we concluded that amyloid kidney transplant recipients are more prone to neuromyopathy than the general kidney transplant population, which is mostly due to the amyloidosis itself and/or the colchicine therapy.
- Subjects
AMYLOIDOSIS treatment; CYCLOSPORINE; KIDNEY disease treatments; IMMUNOSUPPRESSIVE agents; COLCHICINE; GOUT suppressants; AMYLOIDOSIS; CREATINE kinase; ELECTROMYOGRAPHY; EVOKED potentials (Electrophysiology); KIDNEY diseases; KIDNEY transplantation; LACTATE dehydrogenase; NEUROMUSCULAR diseases; DISEASE complications; THERAPEUTICS
- Publication
American Journal of Nephrology, 1996, Vol 16, Issue 2, p114
- ISSN
0250-8095
- Publication type
journal article
- DOI
10.1159/000168981