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- Title
Indirect methods for the diagnosis of aluminum bone disease: Plasma aluminum, the desferrioxamine infusion test, and serum iPTH.
- Authors
Nebeker, Henry G.; Andress, Dennis L.; Milliner, Dawn S.; Ott, Susan M.; Alfrey, Allen C.; Slatopolsky, Eduardo A.; Sherrard, Donald J.; Coburn, Jack W.
- Abstract
Evaluates a noninvasive test based upon the ability of desferrioxamine (DFO) to chelate tissue aluminum, as an indirect method for the diagnosis of aluminum bone disease. Use of a desferrioxamine chelation test to estimate tissue levels of iron and identify patients with iron storage disease; Principal features of aluminum-related bone disease (ABD); Indication that the baseline plasma aluminum level, although correlated with bone aluminum, is not an accurate predictor of ABD; Usefulness of the DFO infusion test in identifying patients with ADB.
- Subjects
BONE diseases; ALUMINUM; DEFEROXAMINE; AMINES; IRON chelates; MICROBIAL metabolites; CHELATES; COORDINATION compounds
- Publication
Kidney International Supplement, 1986, Issue 18, pS-96
- ISSN
0098-6577
- Publication type
Article
- DOI
10.1111/1523-1755.ep14955652