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Dynamic Profiling of Insulin Secretion and ATP Generation in Isolated Human and Mouse Islets Reveals Differential Glucose Sensitivity.
Published in:
Cellular Physiology & Biochemistry (Karger AG), 2017, v. 44, n. 4, p. 1352, doi. 10.1159/000485532
By:
- Pingitore, Attilio;
- Ruz-Maldonado, Inmaculada;
- Liu, Bo;
- Huang, Guo Cai;
- Choudhary, Pratik;
- Persaud, Shanta J.
Publication type:
Article
Neuropeptide Neuromedin B does not alter body weight and glucose homeostasis nor does it act as an insulin-releasing peptide.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-13060-0
By:
- Cikes, Domagoj;
- Atanes, Patricio;
- Cronin, Shane J. F.;
- Hagelkrüys, Astrid;
- Huang, Guo-Cai;
- Persaud, Shanta J.;
- Penninger, Josef M.
Publication type:
Article
CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope.
Published in:
2008
By:
- Skowera, Ania;
- Ellis, Richard J.;
- Varela-Calviño, Ruben;
- Arif, Sefina;
- Guo Cai Huang;
- Van-Krinks, Cassie;
- Zaremba, Anna;
- Rackham, Chloe;
- Allen, Jennifer S.;
- Tree, Timothy I. M.;
- Min Zhao;
- Dayan, Colin M.;
- Sewell, Andrew K.;
- Unger, Wendy;
- Drijfhout, Jan W.;
- Ossendorp, Ferry;
- Roep, Bart O.;
- Peakman, Mark;
- Varela-Calviño, Ruben;
- Huang, Guo Cai
Publication type:
journal article
Costus Pictus Extracts Stimulate Insulin Secretion from Mouse and Human Islets of Langerhans In Vitro.
Published in:
Cellular Physiology & Biochemistry (Karger AG), 2010, v. 26, n. 6, p. 1051, doi. 10.1159/000324007
By:
- Al-Romaiyan, Altaf;
- Jayasri, Mangalam A.;
- Mathew, T. Lazar;
- Huang, Guo-Cai;
- Amiel, Stephanie;
- Jones, Peter M.;
- Persaud, Shanta J.
Publication type:
Article
Characterization of the Effects of Mesenchymal Stromal Cells on Mouse and Human Islet Function.
Published in:
Stem Cells Translational Medicine, 2019, v. 8, n. 9, p. 935, doi. 10.1002/sctm.19-0023
By:
- Arzouni, Ahmed A.;
- Vargas‐Seymour, Andreia;
- Dhadda, Paramjeet K.;
- Rackham, Chloe L.;
- Huang, Guo‐Cai;
- Choudhary, Pratik;
- King, Aileen J. F.;
- Jones, Peter M.
Publication type:
Article
GLP-1 and glucagon secretion from a pancreatic neuroendocrine tumor causing diabetes and hyperinsulinemic hypoglycemia.
Published in:
2012
By:
- Roberts RE;
- Zhao M;
- Whitelaw BC;
- Ramage J;
- Diaz-Cano S;
- le Roux CW;
- Quaglia A;
- Huang GC;
- Aylwin SJ;
- Roberts, Rachel E;
- Zhao, Min;
- Whitelaw, Ben C;
- Ramage, John;
- Diaz-Cano, Salvador;
- le Roux, Carel W;
- Quaglia, Alberto;
- Huang, Guo Cai;
- Aylwin, Simon J B
Publication type:
journal article
A comparative analysis of human and mouse islet G-protein coupled receptor expression.
Published in:
Scientific Reports, 2017, p. 46600, doi. 10.1038/srep46600
By:
- Amisten, Stefan;
- Atanes, Patricio;
- Hawkes, Ross;
- Ruz-Maldonado, Inmaculada;
- Liu, Bo;
- Parandeh, Fariborz;
- Zhao, Min;
- Huang, Guo Cai;
- Salehi, Albert;
- Persaud, Shanta J.
Publication type:
Article
Cover Image, Volume 20, Issue 4.
Published in:
Diabetes, Obesity & Metabolism, 2018, v. 20, n. 4, p. i, doi. 10.1111/dom.13540
By:
- Ruz‐Maldonado, Inmaculada;
- Pingitore, Attilio;
- Liu, Bo;
- Atanes, Patricio;
- Huang, Guo Cai;
- Persaud, Shanta J.;
- Baker, David;
- Alonso, Francisco José;
- Bermúdez‐Silva, Francisco Javier
Publication type:
Article
LH‐21 and abnormal cannabidiol improve β‐cell function in isolated human and mouse islets through GPR55‐dependent and ‐independent signalling.
Published in:
Diabetes, Obesity & Metabolism, 2018, v. 20, n. 4, p. 930, doi. 10.1111/dom.13180
By:
- Ruz‐Maldonado, Inmaculada;
- Pingitore, Attilio;
- Liu, Bo;
- Atanes, Patricio;
- Huang, Guo Cai;
- Persaud, Shanta J.;
- Baker, David;
- Alonso, Francisco José;
- Bermúdez‐Silva, Francisco Javier
Publication type:
Article
Cover Image, Volume 20, Issue 3.
Published in:
2018
By:
- Franklin, Zara J.;
- Tsakmaki, Anastasia;
- Fonseca Pedro, Patricia;
- King, Aileen J.;
- Huang, Guo Cai;
- Amjad, Sakeena;
- Persaud, Shanta J.;
- Bewick, Gavin A.
Publication type:
Cover Art
Islet neuropeptide Y receptors are functionally conserved and novel targets for the preservation of beta‐cell mass.
Published in:
Diabetes, Obesity & Metabolism, 2018, v. 20, n. 3, p. 599, doi. 10.1111/dom.13119
By:
- Franklin, Zara J.;
- Tsakmaki, Anastasia;
- Fonseca Pedro, Patricia;
- King, Aileen J.;
- Huang, Guo Cai;
- Amjad, Sakeena;
- Persaud, Shanta J.;
- Bewick, Gavin A.
Publication type:
Article
Reduced ability of transforming growth factor-alpha to induce EGF receptor heterodimerization and downregulation suggests a mechanism of oncogenic synergy with ErbB2.
Published in:
Oncogene, 1997, v. 15, n. 18, p. 2219, doi. 10.1038/sj.onc.1201595
By:
- Gulliford, Timothy J;
- Huang, Guo Cai;
- Ouyang, Xiaomei;
- Epstein, Richard J
Publication type:
Article
The cannabinoid ligands SR141716A and AM251 enhance human and mouse islet function via GPR55-independent signalling.
Published in:
Cellular & Molecular Life Sciences, 2020, v. 77, n. 22, p. 4709, doi. 10.1007/s00018-019-03433-6
By:
- Ruz-Maldonado, Inmaculada;
- Liu, Bo;
- Atanes, Patricio;
- Pingitore, Attilio;
- Huang, Guo Cai;
- Choudhary, Pratik;
- Persaud, Shanta J.
Publication type:
Article
Defining G protein-coupled receptor peptide ligand expressomes and signalomes in human and mouse islets.
Published in:
Cellular & Molecular Life Sciences, 2018, v. 75, n. 16, p. 3039, doi. 10.1007/s00018-018-2778-z
By:
- Atanes, Patricio;
- Ruz-Maldonado, Inmaculada;
- Hawkes, Ross;
- Liu, Bo;
- Zhao, Min;
- Huang, Guo Cai;
- Al-Amily, Israa Mohammed;
- Salehi, Albert;
- Amisten, Stefan;
- Persaud, Shanta J.
Publication type:
Article
C3aR and C5aR1 act as key regulators of human and mouse β-cell function.
Published in:
Cellular & Molecular Life Sciences, 2018, v. 75, n. 4, p. 715, doi. 10.1007/s00018-017-2655-1
By:
- Atanes, Patricio;
- Ruz-Maldonado, Inmaculada;
- Pingitore, Attilio;
- Hawkes, Ross;
- Liu, Bo;
- Zhao, Min;
- Huang, Guo Cai;
- Persaud, Shanta J.;
- Amisten, Stefan
Publication type:
Article
The Role of Arachidonic Acid and Its Metabolites in Insulin Secretion From Human Islets of Langerhans.
Published in:
Diabetes, 2007, v. 56, n. 1, p. 197, doi. 10.2337/db06-0490
By:
- Persaud, Shanta J.;
- Muller, Dany;
- Belin, Véronique D.;
- Kitsou-Mylona, Isidora;
- Asare-Anane, Henry;
- Papadimitriou, Alexandros;
- Burns, Chris J.;
- Huang, Guo Cai;
- Amiel, Stephanie A.;
- Jones, Peter M.
Publication type:
Article
Different regulated expression of the tyrosine phosphatase-like proteins IA-2 and phogrin by glucose and insulin in pancreatic islets: relationship to development of insulin secretory responses in early life.
Published in:
2002
By:
- Löbner, Kristian;
- Steinbrenner, Holger;
- Roberts, Graham A.;
- Ling, Zhidong;
- Huang, Guo-Cai;
- Piquer, Sandra;
- Pipeleers, Daniel G.;
- Seissler, Jochen;
- Christie, Michael R.;
- Löbner, Kristian
Publication type:
journal article
Direct Stimulatory Effects of the CB 2 Ligand JTE 907 in Human and Mouse Islets.
Published in:
Cells (2073-4409), 2021, v. 10, n. 3, p. 700, doi. 10.3390/cells10030700
By:
- Ruz-Maldonado, Inmaculada;
- Atanes, Patricio;
- Huang, Guo Cai;
- Liu, Bo;
- Persaud, Shanta J;
- Kalyuzhny, Alexander E.
Publication type:
Article
Expression of mesenchymal and α-cell phenotypic markers in islet β-cells in recently diagnosed diabetes.
Published in:
2013
By:
- White, Michael G;
- Marshall, Helen L;
- Rigby, Rebecca;
- Huang, Guo Cai;
- Amer, Aimen;
- Booth, Trevor;
- White, Steve;
- Shaw, James A M
Publication type:
journal article
Human β-cell killing by autoreactive preproinsulin-specific CD8 T cells is predominantly granule-mediated with the potency dependent upon T-cell receptor avidity.
Published in:
2013
By:
- Knight RR;
- Kronenberg D;
- Zhao M;
- Huang GC;
- Eichmann M;
- Bulek A;
- Wooldridge L;
- Cole DK;
- Sewell AK;
- Peakman M;
- Skowera A;
- Knight, Robin R;
- Kronenberg, Deborah;
- Zhao, Min;
- Huang, Guo Cai;
- Eichmann, Martin;
- Bulek, Anna;
- Wooldridge, Linda;
- Cole, David K;
- Sewell, Andrew K
Publication type:
journal article
Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death.
Published in:
Diabetes, 2011, v. 60, n. 8, p. 2112, doi. 10.2337/db10-1643
By:
- Arif, Sefina;
- Moore, Fabrice;
- Marks, Katherine;
- Bouckenooghe, Thomas;
- Dayan, Colin M.;
- Planas, Raquel;
- Vives-Pi, Marta;
- Powrie, Jake;
- Tree, Timothy;
- Marchetti, Piero;
- Huang, Guo Cai;
- Gurzov, Esteban N.;
- Pujol-Borrell, Ricardo;
- Eizirik, Decio L.;
- Peakman, Mark
Publication type:
Article

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