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- Title
Haemocyte Apoptosis of the Tiger Shrimp Penaeus monodon Exposed to Cadmium.
- Authors
Xian, Jian-An; Li, Bin; Guo, Hui; Miao, Yu-Tao; Ye, Jian-Min; Feng, Li-Na; Ye, Chao-Xia; Pan, Xun-Bin; Wang, An-Li; Hao, Xuan-Ming
- Abstract
This study investigated the effect of ambient Cadmium (Cd) on haemocyte apoptosis of the shrimp, Penaeus monodon. Cellular response was determined in Cd-exposed (0, 0.05, 0.5 and 5 mg L) shrimp. Results showed that 0.05 mg L Cd had no significant effect on the haemocyte parameters during the 48 h exposure. Cadmium at doses of 0.5 and 5 mg L depressed the total haemocyte count (THC), and increased reactive oxygen species (ROS) production and apoptosis ratio in haemocytes. Esterase activity increased in shrimp exposed to 0.5 mg L Cd for 6 h, and decreased to the initial level later. Depressed esterase activity could be observed in shrimp after 24 and 48 h exposure to 5 mg L Cd. These results demonstrated that Cd modified esterase activity and induced ROS generation, which led to haemocyte apoptosis and THC reduction. Oxidative stress is one of the induction mechanisms for Cd-caused apoptosis of shrimp haemocytes.
- Subjects
BLOOD cells; APOPTOSIS; PENAEUS japonicus; CADMIUM poisoning; PHYSIOLOGICAL effects of cadmium; FLOW cytometry; REACTIVE oxygen species
- Publication
Bulletin of Environmental Contamination & Toxicology, 2014, Vol 92, Issue 5, p525
- ISSN
0007-4861
- Publication type
Article
- DOI
10.1007/s00128-013-1165-6