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- Title
Long-Term Mortality in a Cohort of Home-Dwelling Elderly with Mild Alzheimer's Disease and Lewy Body Dementia.
- Authors
Oesterhus, Ragnhild; Soennesyn, Hogne; Rongve, Arvid; Ballard, Clive; Aarsland, Dag; Vossius, Corinna
- Abstract
Objective: To study mortality in subjects with mild dementia in Norway with a special focus on patients with Lewy body dementia (LBD) compared to Alzheimer's disease (AD). Methods: All referrals of mild dementia patients to dementia clinics in western Norway from March 2005 to March 2007 were included and followed until December 2012. Diagnoses were based on a comprehensive standardized assessment program. Results: Of 209 patients, 137 (66%) had AD and 53 (25%) had LBD. Dementia was associated with increased mortality (standardized mortality ratio = 1.8, AD 1.5, LBD 2.6). The median survival time was 6.2 years (95% CI 5.4-6.9). Predictors of mortality were age at diagnosis (HR 1.1 per year) and LBD diagnosis (HR 2.4). Conclusion: Dementia patients had an increased mortality, particularly those with LBD. © 2014 S. Karger AG, Basel
- Subjects
NORWAY; ALZHEIMER'S disease; ANALYSIS of variance; BLOOD testing; CHI-squared test; COMPARATIVE studies; CONFIDENCE intervals; DEMENTIA; FISHER exact test; INTERVIEWING; LEWY body dementia; LONGITUDINAL method; RESEARCH methodology; REGRESSION analysis; T-test (Statistics); U-statistics; DATA analysis software; DESCRIPTIVE statistics; KAPLAN-Meier estimator; LOG-rank test; DISEASE complications
- Publication
Dementia & Geriatric Cognitive Disorders, 2014, Vol 38, Issue 3/4, p161
- ISSN
1420-8008
- Publication type
Article
- DOI
10.1159/000358051