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Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans.
Published in:
Journal of Clinical Investigation, 2004, v. 114, n. 8, p. 1158, doi. 10.1172/JCI200421927
By:
- Srinivasan, Supriya;
- Lubrano-Berthelier, Cecile;
- Govaerts, Cedric;
- Picard, Franck;
- Santiago, Pamela;
- Conklin, Bruce R.;
- Vaisse, Christian
Publication type:
Article
Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans.
Published in:
2004
By:
- Srinivasan, Supriya;
- Lubrano-Berthelier, Cecile;
- Govaerts, Cedric;
- Picard, Franck;
- Santiago, Pamela;
- Conklin, Bruce R;
- Vaisse, Christian
Publication type:
journal article
LINE-1 ORF1p as a candidate biomarker in high grade serous ovarian carcinoma.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-28840-5
By:
- Sato, Sho;
- Gillette, Michael;
- de Santiago, Pamela R.;
- Kuhn, Eric;
- Burgess, Michael;
- Doucette, Kristen;
- Feng, Yi;
- Mendez-Dorantes, Carlos;
- Ippoliti, Paul J.;
- Hobday, Sara;
- Mitchell, Marilyn A.;
- Doberstein, Kai;
- Gysler, Stefan M.;
- Hirsch, Michelle S.;
- Schwartz, Lauren;
- Birrer, Michael J.;
- Skates, Steven J.;
- Burns, Kathleen H.;
- Carr, Steven A.;
- Drapkin, Ronny
Publication type:
Article
Variable effects of the gamma-secretase inhibitor ELND006 on Aβ across different compartments (brain, ISF, CSF, and plasma) following sustained exposure via subcutaneous osmotic pumps in wild-type mice
Published in:
2011
By:
- Brigham, Elizabeth;
- Wong, Angelina;
- Rampurna, Gullapalli;
- Quinn, Kevin;
- Kwong, Grace;
- Willits, Christopher;
- Wadsworth, Angie;
- Dofiles, Lilibeth;
- San Pablo, Florentino;
- Chian, David;
- Santiago, Pamela;
- Hoffman, Jennifer;
- Cirrito, John;
- Restivo, Jessica;
- Goldbach, Erich;
- Motter, Ruth;
- Wallace, William;
- Kinney, Gene;
- Ness, Daniel
Publication type:
Abstract
Pharmacokinetic and pharmacodynamic investigation of ELND006, a novel APP-selective gamma-secretase inhibitor, on amyloid-β concentrations in the brain, CSF and plasma of multiple nonclinical species following oral administration
Published in:
2010
By:
- Brigham, Elizabeth;
- Quinn, Kevin;
- Kwong, Grace;
- Willits, Chris;
- Goldbach, Erich;
- Motter, Ruth;
- Lee, Michael;
- Hu, Kang;
- Wallace, William;
- Kholodenko, Dora;
- Tang-Tanaka, Pearl;
- Ni, Huifang;
- Hemphill, Susanna;
- Chen, Xiao-hua;
- Eichenbaum, Tovah;
- Ruslim, Lany;
- Nguyen, Lan;
- Santiago, Pamela;
- Liao, Anna;
- Bova, Michael
Publication type:
Abstract
Pharmacokinetic and pharmacodynamic analysis of a novel gamma secretase inhibitor in a nontransgenic A-beta mouse efficacy model
Published in:
2009
By:
- Quinn, Kevin P.;
- Kuwabara-Wagg, Jonathan;
- Brigham, Elizabeth;
- Cabrera, Cristian;
- Goldbach, Erich;
- Dreyer, Mark;
- Hu, Kang;
- Lee, Mike;
- Green, Michelle;
- Ness, Daniel;
- Santiago, Pamela;
- Samant, Bhushan;
- Soriano, Ferdie;
- Webb, Steve;
- Basi, Guriqbal S.;
- Sauer, John-Michael
Publication type:
Abstract
Pharmacokinetic and pharmacodynamic analysis of a novel gamma secretase inhibitor in a non-transgenic A-beta mouse efficacy model
Published in:
2009
By:
- Quinn, Kevin P.;
- Kuwabara-Wagg, Jonathan;
- Brigham, Elizabeth;
- Cabrera, Cristian;
- Goldbach, Erich;
- Dreyer, Mark;
- Hu, Kang;
- Lee, Mike;
- Green, Michelle;
- Ness, Daniel;
- Santiago, Pamela;
- Samant, Bhushan;
- Soriano, Ferdie;
- Webb, Steve;
- Basi, Guriqbal S.;
- Sauer, John-Michael
Publication type:
Abstract
Total mutational load and clinical features as predictors of the metastatic status in lung adenocarcinoma and squamous cell carcinoma patients.
Published in:
2022
By:
- Oróstica, Karen Y.;
- Saez-Hidalgo, Juan;
- de Santiago, Pamela R.;
- Rivas, Solange;
- Contreras, Sebastian;
- Navarro, Gonzalo;
- Asenjo, Juan A.;
- Olivera-Nappa, Álvaro;
- Armisén, Ricardo
Publication type:
journal article
Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis.
Published in:
Liver International, 2015, v. 35, n. 9, p. 2129, doi. 10.1111/liv.12794
By:
- Pizarro, Margarita;
- Solís, Nancy;
- Quintero, Pablo;
- Barrera, Francisco;
- Cabrera, Daniel;
- Rojas‐de Santiago, Pamela;
- Arab, Juan P.;
- Padilla, Oslando;
- Roa, Juan C.;
- Moshage, Han;
- Wree, Alexander;
- Inzaugarat, Eugenia;
- Feldstein, Ariel E.;
- Fardella, Carlos E.;
- Baudrand, Rene;
- Riquelme, Arnoldo;
- Arrese, Marco
Publication type:
Article

Found: 9