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- Title
Recovery of severe dialysis disequilibrium syndrome with uncal herniation following therapy with mannitol, hyperventilation and hypertonic saline.
- Authors
Liu, Kuan-Hung; Lee, Shao-Hua; Lin, Wei-Ren; Tsai, Yau-Sheng; Sung, Junne-Ming
- Abstract
Dialysis disequilibrium syndrome (DDS) is a rare complication of dialysis, especially with the general application of preventive strategies. Severe DDS with brain herniation is believed to be fatal. We present a patient presenting with bilateral uncal herniation after receiving two dialysis sessions with low-efficiency settings. Serial brain magnetic resonance imaging studies showed the temporal evolution of DDS-induced cerebral edema. With aggressive treatment of hypertonic saline and mannitol, the patient made a remarkable recovery. This case highlights that we should be cautious about this severe complication of dialysis even with preventive strategies, and recovery is possible with prompt recognition and treatment.
- Subjects
HYPERTONIC saline solutions; HYPERVENTILATION; HERNIA; DIALYSIS (Chemistry); MANNITOL; HEMODIALYSIS
- Publication
Clinical Kidney Journal, 2022, Vol 15, Issue 1, p165
- ISSN
2048-8505
- Publication type
Article
- DOI
10.1093/ckj/sfab165