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- Title
Concordance for Gender Dysphoria in Genetic Female Monozygotic (Identical) Triplets.
- Authors
Kauffman, Robert P.; Guerra, Carly; Thompson, Christopher M.; Stark, Amy
- Abstract
The biopsychosocial etiology of gender dysphoria is poorly understood, but current thought suggests a complex interaction of genetic, hormonal, environmental, and differences in brain development and physiology. Twin studies have implicated a genetic role in the formation of gender identity. Congruence for gender dysphoria is more common among monozygotic twins compared to dizygotic twins. We present a case of monozygotic (identical) triplets who have each transitioned from female to male under the care of a university transgender health service. Each triplet experienced gender dysphoria from childhood and has undergone transitional endocrine care and various aspects of gender-affirming surgery. Although a pure genetic or biological component cannot be attributed as a cause of their gender dysphoria with absolute certainty since the triplets were raised together, this unusual case of gender dysphoria among a set of monozygotic triplets adds support for a heritable role in gender identity formation.
- Publication
Archives of Sexual Behavior, 2022, Vol 51, Issue 7, p3647
- ISSN
0004-0002
- Publication type
journal article
- DOI
10.1007/s10508-022-02409-1