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Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.
Published in:
Nature Medicine, 2015, v. 21, n. 5, p. 530, doi. 10.1038/nm.3848
By:
- Ilkow, Carolina S;
- Marguerie, Monique;
- Batenchuk, Cory;
- Mayer, Justin;
- Ben Neriah, Daniela;
- Cousineau, Sophie;
- Falls, Theresa;
- Jennings, Victoria A;
- Boileau, Meaghan;
- Bellamy, David;
- Bastin, Donald;
- de Souza, Christiano Tanese;
- Alkayyal, Almohanad;
- Zhang, Jiqing;
- Le Boeuf, Fabrice;
- Arulanandam, Rozanne;
- Stubbert, Lawton;
- Sampath, Padma;
- Thorne, Steve H;
- Paramanthan, Piriya
Publication type:
Article
Different ODE models of tumor growth can deliver similar results.
Published in:
2020
By:
- Koziol, James A;
- Falls, Theresa J;
- Schnitzer, Jan E
Publication type:
journal article
Enhancement of Vaccinia Virus Based Oncolysis with Histone Deacetylase Inhibitors.
Published in:
PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0014462
By:
- MacTavish, Heather;
- Diallo, Jean-Simon;
- Huang, Baocheng;
- Stanford, Marianne;
- Boeuf, Fabrice Le;
- Silva, Naomi De;
- Cox, Julie;
- Simmons, John Graydon;
- Guimond, Tanya;
- Falls, Theresa;
- McCart, J. Andrea;
- Atkins, Harry;
- Breitbach, Caroline;
- Kirn, David;
- Thorne, Stephen;
- Bell, John C.
Publication type:
Article
Molecular Characterization and Xenotransplantation of Pancreatic Cancer Using Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA).
Published in:
Cancers, 2024, v. 16, n. 15, p. 2721, doi. 10.3390/cancers16152721
By:
- Antonova, Lilia;
- Paramanthan, Piriya;
- Falls, Theresa;
- Wedge, Marie-Eve;
- Mayer, Justin;
- Sekhon, Harman S.;
- McPherson, John;
- Denroche, Robert E.;
- Gallinger, Steven;
- Bell, John Cameron;
- Ilkow, Carolina S.;
- Chatterjee, Avijit
Publication type:
Article
Complement Inhibition Prevents Oncolytic Vaccinia Virus Neutralization in Immune Humans and Cynomolgus Macaques.
Published in:
Molecular Therapy, 2015, v. 23, n. 6, p. 1066, doi. 10.1038/mt.2015.49
By:
- Evgin, Laura;
- Acuna, Sergio A;
- Tanese de Souza, Christiano;
- Marguerie, Monique;
- Lemay, Chantal G;
- Ilkow, Carolina S;
- Findlay, C Scott;
- Falls, Theresa;
- Parato, Kelley A;
- Hanwell, David;
- Goldstein, Alyssa;
- Lopez, Roberto;
- Lafrance, Sandra;
- Breitbach, Caroline J;
- Kirn, David;
- Atkins, Harold;
- Auer, Rebecca C;
- Thurman, Joshua M;
- Stahl, Gregory L;
- Lambris, John D
Publication type:
Article
Maraba MG1 Virus Enhances Natural Killer Cell Function via Conventional Dendritic Cells to Reduce Postoperative Metastatic Disease.
Published in:
Molecular Therapy, 2014, v. 22, n. 7, p. 1320, doi. 10.1038/mt.2014.60
By:
- Zhang, Jiqing;
- Tai, Lee-Hwa;
- Ilkow, Carolina S;
- Alkayyal, Almohanad A;
- Ananth, Abhirami A;
- de Souza, Christiano Tanese;
- Wang, Jiahu;
- Sahi, Shalini;
- Ly, Lundi;
- Lefebvre, Charles;
- Falls, Theresa J;
- Stephenson, Kyle B;
- Mahmoud, Ahmad B;
- Makrigiannis, Andrew P;
- Lichty, Brian D;
- Bell, John C;
- Stojdl, David F;
- Auer, Rebecca C
Publication type:
Article
Bacterial-Mediated Knockdown of Tumor Resistance to an Oncolytic Virus Enhances Therapy.
Published in:
Molecular Therapy, 2014, v. 22, n. 6, p. 1188, doi. 10.1038/mt.2014.23
By:
- Cronin, Michelle;
- Le Boeuf, Fabrice;
- Murphy, Carola;
- Roy, Dominic G;
- Falls, Theresa;
- Bell, John C;
- Tangney, Mark
Publication type:
Article
Harnessing Oncolytic Virus-mediated Antitumor Immunity in an Infected Cell Vaccine.
Published in:
Molecular Therapy, 2012, v. 20, n. 9, p. 1791, doi. 10.1038/mt.2012.128
By:
- Lemay, Chantal G;
- Rintoul, Julia L;
- Kus, Agnieszka;
- Paterson, Jennifer M;
- Garcia, Vanessa;
- Falls, Theresa J;
- Ferreira, Lisa;
- Bridle, Byram W;
- Conrad, David P;
- Tang, Vera A;
- Diallo, Jean-Simon;
- Arulanandam, Rozanne;
- Le Boeuf, Fabrice;
- Garson, Kenneth;
- Vanderhyden, Barbara C;
- Stojdl, David F;
- Lichty, Brian D;
- Atkins, Harold L;
- Parato, Kelley A;
- Bell, John C
Publication type:
Article
ORFV: A Novel Oncolytic and Immune Stimulating Parapoxvirus Therapeutic.
Published in:
Molecular Therapy, 2012, v. 20, n. 6, p. 1148, doi. 10.1038/mt.2011.301
By:
- Rintoul, Julia L;
- Lemay, Chantal G;
- Tai, Lee-Hwa;
- Stanford, Marianne M;
- Falls, Theresa J;
- de Souza, Christiano T;
- Bridle, Byram W;
- Daneshmand, Manijeh;
- Ohashi, Pamela S;
- Wan, Yonghong;
- Lichty, Brian D;
- Mercer, Andrew A;
- Auer, Rebecca C;
- Atkins, Harold L;
- Bell, John C
Publication type:
Article
Combination of Paclitaxel and MG1 oncolytic virus as a successful strategy for breast cancer treatment.
Published in:
2016
By:
- Bourgeois-Daigneault, Marie-Claude;
- St-Germain, Lauren Elizabeth;
- Roy, Dominic Guy;
- Pelin, Adrian;
- Aitken, Amelia Sadie;
- Arulanandam, Rozanne;
- Falls, Theresa;
- Garcia, Vanessa;
- Diallo, Jean-Simon;
- Bell, John Cameron
Publication type:
journal article
Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing.
Published in:
Nature Communications, 2015, v. 6, n. 3, p. 6410, doi. 10.1038/ncomms7410
By:
- Arulanandam, Rozanne;
- Batenchuk, Cory;
- Varette, Oliver;
- Zakaria, Chadi;
- Garcia, Vanessa;
- Forbes, Nicole E.;
- Davis, Colin;
- Krishnan, Ramya;
- Karmacharya, Raunak;
- Cox, Julie;
- Sinha, Anisha;
- Babawy, Andrew;
- Waite, Katherine;
- Weinstein, Erica;
- Falls, Theresa;
- Chen, Andrew;
- Hamill, Jeff;
- De Silva, Naomi;
- Conrad, David P.;
- Atkins, Harold
Publication type:
Article
Model-based rational design of an oncolytic virus with improved therapeutic potential.
Published in:
Nature Communications, 2013, v. 4, n. 6, p. 1974, doi. 10.1038/ncomms2974
By:
- Le Bœuf, Fabrice;
- Batenchuk, Cory;
- Vähä-Koskela, Markus;
- Breton, Sophie;
- Roy, Dominic;
- Lemay, Chantal;
- Cox, Julie;
- Abdelbary, Hesham;
- Falls, Theresa;
- Waghray, Girija;
- Atkins, Harold;
- Stojdl, David;
- Diallo, Jean-Simon;
- Kærn, Mads;
- Bell, John C.
Publication type:
Article
Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy.
Published in:
Science Translational Medicine, 2018, v. 10, n. 422, p. 1, doi. 10.1126/scitranslmed.aao1641
By:
- Bourgeois-Daigneault, Marie-Claude;
- Roy, Dominic Guy;
- Aitken, Amelia Sadie;
- El Sayes, Nader;
- Martin, Nikolas Tim;
- Varette, Oliver;
- Falls, Theresa;
- St-Germain, Lauren Elizabeth;
- Pelin, Adrian;
- Lichty, Brian Dennis;
- Stojdl, David Francis;
- Ungerechts, Guy;
- Diallo, Jean-Simon;
- Bell, John Cameron
Publication type:
Article
Enhancing Expression of Functional Human Sodium Iodide Symporter and Somatostatin Receptor in Recombinant Oncolytic Vaccinia Virus for In Vivo Imaging of Tumors.
Published in:
Journal of Nuclear Medicine, 2017, v. 58, n. 2, p. 221, doi. 10.2967/jnumed.116.180463
By:
- Jiahu Wang;
- Arulanandam, Rozanne;
- Wassenaar, Richard;
- Falls, Theresa;
- Petryk, Julia;
- Paget, Judith;
- Garson, Kenneth;
- Cemeus, Catia;
- Vanderhyden, Barbara C.;
- Wells, R. Glenn;
- Bell, John C.;
- Boeuf, Fabrice Le
Publication type:
Article
Oncolytic Vaccinia virus safely and effectively treats skin tumors in mouse models of xeroderma pigmentosum.
Published in:
International Journal of Cancer, 2013, v. 132, n. 3, p. 726, doi. 10.1002/ijc.27695
By:
- Brun, Jan;
- Mahoney, Douglas J.;
- Le Boeuf, Fabrice;
- Lefebvre, Charles;
- Sanaei, Cina A.;
- Falls, Theresa;
- Mccart, J. Andrea;
- Stojdl, David F.
Publication type:
Article
Adenovirus-Mediated Expression of the p14 Fusion-Associated Small Transmembrane Protein Promotes Cancer Cell Fusion and Apoptosis In Vitro but Does Not Provide Therapeutic Efficacy in a Xenograft Mouse Model of Cancer.
Published in:
PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0151516
By:
- Wong, Carmen M.;
- Poulin, Kathy L.;
- Tong, Grace;
- Christou, Carin;
- Kennedy, Michael A.;
- Falls, Theresa;
- Bell, John C.;
- Parks, Robin J.
Publication type:
Article
The Oncolytic Poxvirus JX-594 Selectively Replicates in and Destroys Cancer Cells Driven by Genetic Pathways Commonly Activated in Cancers.
Published in:
Molecular Therapy, 2012, v. 20, n. 4, p. 749, doi. 10.1038/mt.2011.276
By:
- Parato, Kelley A;
- Breitbach, Caroline J;
- Le Boeuf, Fabrice;
- Wang, Jiahu;
- Storbeck, Chris;
- Ilkow, Carolina;
- Diallo, Jean-Simon;
- Falls, Theresa;
- Burns, Joseph;
- Garcia, Vanessa;
- Kanji, Femina;
- Evgin, Laura;
- Hu, Kang;
- Paradis, Francois;
- Knowles, Shane;
- Hwang, Tae-Ho;
- Vanderhyden, Barbara C;
- Auer, Rebecca;
- Kirn, David H;
- Bell, John C
Publication type:
Article
Sequential Therapy With JX-594, A Targeted Oncolytic Poxvirus, Followed by Sorafenib in Hepatocellular Carcinoma: Preclinical and Clinical Demonstration of Combination Efficacy.
Published in:
Molecular Therapy, 2011, v. 19, n. 6, p. 1170, doi. 10.1038/mt.2011.39
By:
- Heo, Jeong;
- Breitbach, Caroline J;
- Moon, Anne;
- Kim, Chang Won;
- Patt, Rick;
- Kim, Mi Kyung;
- Lee, Yu Kyung;
- Oh, Sung Yong;
- Woo, Hyun Young;
- Parato, Kelley;
- Rintoul, Julia;
- Falls, Theresa;
- Hickman, Theresa;
- Rhee, Byung-Geon;
- Bell, John C;
- Kirn, David H;
- Hwang, Tae-Ho
Publication type:
Article
Targeting Tumor Vasculature With an Oncolytic Virus.
Published in:
Molecular Therapy, 2011, v. 19, n. 5, p. 886, doi. 10.1038/mt.2011.26
By:
- Breitbach, Caroline J;
- De Silva, Naomi S;
- Falls, Theresa J;
- Aladl, Usaf;
- Evgin, Laura;
- Paterson, Jennifer;
- Sun, Yang Yang;
- Roy, Dominic G;
- Rintoul, Julia L;
- Daneshmand, Manijeh;
- Parato, Kelley;
- Stanford, Marianne M;
- Lichty, Brian D;
- Fenster, Aaron;
- Kirn, David;
- Atkins, Harold;
- Bell, John C
Publication type:
Article
Identification of Genetically Modified Maraba Virus as an Oncolytic Rhabdovirus.
Published in:
Molecular Therapy, 2010, v. 18, n. 8, p. 1440, doi. 10.1038/mt.2010.103
By:
- Brun, Jan;
- McManus, Dan;
- Lefebvre, Charles;
- Kang Hu;
- Falls, Theresa;
- Atkins, Harold;
- Bell, John C.;
- McCart, J. Andrea;
- Mahoney, Douglas;
- Stojdl, David F.
Publication type:
Article
A High-throughput Pharmacoviral Approach Identifies Novel Oncolytic Virus Sensitizers.
Published in:
Molecular Therapy, 2010, v. 18, n. 6, p. 1123, doi. 10.1038/mt.2010.67
By:
- Diallo, Jean-Simon;
- Le Boeuf, Fabrice;
- Lai, Frances;
- Cox, Julie;
- Vaha-Koskela, Markus;
- Abdelbary, Hesham;
- MacTavish, Heather;
- Waite, Katherine;
- Falls, Theresa;
- Wang, Jenny;
- Brown, Ryan;
- Blanchard, Jan E.;
- Brown, Eric D.;
- Kirn, David H.;
- Hiscott, John;
- Atkins, Harry;
- Lichty, Brian D.;
- Bell, John C.
Publication type:
Article
Potent Oncolytic Activity of Raccoonpox Virus in the Absence of Natural Pathogenicity.
Published in:
Molecular Therapy, 2010, v. 18, n. 5, p. 896, doi. 10.1038/mt.2010.14
By:
- Evgin, Laura;
- Vähä-Koskela, Markus;
- Rintoul, Julia;
- Falls, Theresa;
- Le Boeuf, Fabrice;
- Barrett, John W.;
- Bell, John C.;
- Stanford, Marianne M.
Publication type:
Article
Synergistic Interaction Between Oncolytic Viruses Augments Tumor Killing.
Published in:
Molecular Therapy, 2010, v. 18, n. 5, p. 888, doi. 10.1038/mt.2010.44
By:
- Le Boeuf, Fabrice;
- Diallo, Jean-Simon;
- McCart, J. Andrea;
- Thorne, Steve;
- Falls, Theresa;
- Stanford, Marianne;
- Kanji, Femina;
- Auer, Rebecca;
- Brown, Christopher W.;
- Lichty, Brian D.;
- Parato, Kelley;
- Atkins, Harold;
- Kirn, David;
- Bell, John C.
Publication type:
Article
A let-7 MicroRNA-sensitive Vesicular Stomatitis Virus Demonstrates Tumor-specific Replication.
Published in:
Molecular Therapy, 2008, v. 16, n. 8, p. 1437, doi. 10.1038/mt.2008.130
By:
- Edge, Robert E.;
- Falls, Theresa J.;
- Brown, Christopher W.;
- Lichty, Brian D.;
- Atkins, Harold;
- Bell, John C.
Publication type:
Article
Targeted Inflammation During Oncolytic Virus Therapy Severely Compromises Tumor Blood Flow.
Published in:
Molecular Therapy, 2007, v. 15, n. 9, p. 1686, doi. 10.1038/sj.mt.6300215
By:
- Breitbach, Caroline J.;
- Paterson, Jennifer M.;
- Lemay, Chantal G.;
- Falls, Theresa J.;
- McGuire, Allison;
- Parato, Kelley A.;
- Stojdl, David F.;
- Daneshmand, Manijeh;
- Speth, Kelly;
- Kirn, David;
- McCart, J. Andrea;
- Atkins, Harold;
- Bell, John C.
Publication type:
Article
Carrier Cell-based Delivery of an Oncolytic Virus Circumvents Antiviral Immunity.
Published in:
Molecular Therapy, 2007, v. 15, n. 1, p. 123, doi. 10.1038/sj.mt.6300039
By:
- Power, Anthony T.;
- Wang, Jiahu;
- Falls, Theresa J.;
- Paterson, Jennifer M.;
- Parato, Kelley A.;
- Lichty, Brian D.;
- Stojdl, David F.;
- Forsyth, Peter A. J.;
- Atkins, Harry;
- Bell, John C.
Publication type:
Article
In vivo characterization of [18F]AVT-011 as a radiotracer for PET imaging of multidrug resistance.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2020, v. 47, n. 8, p. 2026, doi. 10.1007/s00259-019-04589-w
By:
- Kannan, Pavitra;
- Füredi, András;
- Dizdarevic, Sabina;
- Wanek, Thomas;
- Mairinger, Severin;
- Collins, Jeffrey;
- Falls, Theresa;
- van Dam, R. Michael;
- Maheshwari, Divya;
- Lee, Jason T.;
- Szakács, Gergely;
- Langer, Oliver
Publication type:
Article

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