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- Title
Cytotoxicity and antimicrobial activity of goniothalamin isolated from Bryonopsis laciniosa.
- Authors
M. Ashik Mosaddik; M. Ekramul Haque
- Abstract
The cytotoxicity and antimicrobial activity of goniothalamin isolated from Bryonopsis laciniosa was investigated. Goniothalamin showed potent cytotoxicity with LC50 values (5.03 µg/mL) comparable with the reference standard agent, gallic acid. It also showed weak antibacterial and significant antifungal activity against a wide range of gram positive and gram negative bacteria and fungi. The antibacterial (minimum inhibitory concentration) effect against Bacillus cereus and Shigella shiga was found to be 64 µg/mL. Copyright © 2003 John Wiley & Sons, Ltd.
- Subjects
ANTI-infective agents; ANTIBACTERIAL agents; ANTIFUNGAL agents; GRAM-positive bacteria; GRAM-negative bacteria; BACILLUS cereus
- Publication
Phytotherapy Research, 2003, Vol 17, Issue 10, p1155
- ISSN
0951-418X
- Publication type
Article
- DOI
10.1002/ptr.1303