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- Title
Acinetobacter infections in pediatric intensive care unit: A single-center experience.
- Authors
Taşkın, Esra Çakmak; Özdemir, Halil; Konca, Hatice Kübra; Arga, Gül; Özcan, Serhan; Havan, Merve; Güriz, Haluk; Kendirli, Tanıl; İnce, Erdal; Çiftçi, Ergin
- Abstract
Objective: The aim of this study is to investigate the risk factors, types of infections, antibiotic resistance patterns, and mortality rates in hospitalized patients with Acinetobacter infections in the pediatric intensive care unit. Material and Methods: The patients who were hospitalized in the pediatric intensive care unit between January 2013 and September 2018 and had Acinetobacter infections were evaluated retrospectively. Results: Eighty-two patients who developed Acinetobacter infections were admitted to the study. Fifty-three (64.6%) of the patients were male. The mean age was 68.9±74.6 months. The majority of patients had underlying diseases. Most patients had a history of invasive procedures: mechanical ventilation (95.1%), central venous catheter (86.6%), and urinary catheter (62.2%). Ventilator-associated pneumonia was the most common diagnosis (57.3%). The majority of Acinetobacter species were resistant to carbapenems (93.9%). Colistin and meropenem were the most common antibiotics used in the treatment of patients, and 15.8% of the isolates were resistant to colistin. The mortality rate on the 30th day of Acinetobacter infection was 35.3%. The most frequent infections in patients who died were ventilator-associated pneumonia and catheter-related bloodstream infection. Conclusion: A. baumannii infections cause high mortality with resistance to antibiotics. When the factors that increase mortality are evaluated and the changeable ones are improved, some of the deaths due to these infections may be decreased. The leading precautions should be avoiding invasive procedures, especially in intensive care units, and the unnecessary use of broad-spectrum antibiotics.
- Subjects
TURKEY; RISK assessment; METABOLIC disorders; CONGENITAL heart disease; ACINETOBACTER infections; DRUG resistance in microorganisms; BLOODBORNE infections; CATHETER-related infections; HOSPITAL mortality; RETROSPECTIVE studies; DESCRIPTIVE statistics; CHI-squared test; MANN Whitney U Test; URINARY catheters; VENTILATOR-associated pneumonia; GRAM-negative aerobic bacteria; COLISTIN; PEDIATRICS; INTENSIVE care units; MEDICAL records; ACQUISITION of data; LUNG diseases; ARTIFICIAL respiration; CENTRAL venous catheters; BACTERIAL diseases; DATA analysis software; TUMORS; CARBAPENEM-resistant bacteria; MEROPENEM; DISEASE risk factors
- Publication
Ümraniye Pediatri Dergisi, 2024, Vol 4, Issue 1, p39
- ISSN
2757-7074
- Publication type
Article
- DOI
10.14744/upd.2024.13008