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- Title
Influence of Obstructive Apnea Index on Persistent Left Ventricular Dysfunction in Patients with ST-Segment Elevation Myocardial Infarction.
- Authors
Kirigaya, Jin; Iwahashi, Noriaki; Ishigami, Tomoaki; Abe, Takeru; Gohbara, Masaomi; Hanajima, Yohei; Horii, Mutsuo; Okada, Kozo; Matsuzawa, Yasushi; Kosuge, Masami; Ebina, Toshiaki; Hibi, Kiyoshi
- Abstract
Background: We retrospectively investigated the effects of the severity and classification of sleep-disordered breathing (SDB) on left ventricular (LV) function in patients with ST-segment elevation myocardial infarction (STEMI). Methods: A total of 115 patients with STEMIs underwent a sleep study using a multichannel frontopolar electroencephalography recording device (Sleep Profiler) one week after STEMI onset. We evaluated LV global longitudinal strain (LV-GLS) using two-dimensional echocardiography at one week and seven months. Patients were classified as no SDB (AHI < 5 events/h), obstructive SDB (over 50% of apnea events are obstructive), and central SDB (over 50% of apnea events are central). Due to the device's limitations in distinguishing obstructive from central hypopnea, SDB classification was based on apnea index percentages. Results: The obstructive apnea index (OAI) was significantly associated with LV-GLS at one week (r = 0.24, p = 0.027) and seven months (r = 0.21, p = 0.020). No such correlations were found for the central apnea index and SDB classification. Multivariable regression analysis showed that the OAI was independently associated with LV-GLS at one week (β = 0.24, p = 0.002) and seven months (β = 0.20, p = 0.008). Conclusions: OAI is associated with persistent LV dysfunction assessed by LV-GLS in STEMI.
- Subjects
ST elevation myocardial infarction; LEFT ventricular dysfunction; GLOBAL longitudinal strain; APNEA; SLEEP apnea syndromes; FETAL echocardiography
- Publication
Journal of Clinical Medicine, 2024, Vol 13, Issue 4, p986
- ISSN
2077-0383
- Publication type
Article
- DOI
10.3390/jcm13040986