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- Title
From Vibrations to Visions: Raman Spectroscopy's Impact on Skin Cancer Diagnostics.
- Authors
Delrue, Charlotte; Speeckaert, Reinhart; Oyaert, Matthijs; De Bruyne, Sander; Speeckaert, Marijn M.
- Abstract
Raman spectroscopy, a non-invasive diagnostic technique capturing molecular vibrations, offers significant advancements in skin cancer diagnostics. This review delineates the ascent of Raman spectroscopy from classical methodologies to the forefront of modern technology, emphasizing its precision in differentiating between malignant and benign skin tissues. Our study offers a detailed examination of distinct Raman spectroscopic signatures found in skin cancer, concentrating specifically on squamous cell carcinoma, basal cell carcinoma, and melanoma, across both in vitro and in vivo research. The discussion extends to future possibilities, spotlighting enhancements in portable Raman instruments, the adoption of machine learning for spectral data refinement, and the merging of Raman imaging with other diagnostic techniques. The review culminates by contemplating the broader implications of these advancements, suggesting a trajectory that may significantly optimize the accuracy and efficiency of skin cancer diagnostics.
- Subjects
SKIN cancer; RAMAN spectroscopy; BASAL cell carcinoma; MOLECULAR vibration; SQUAMOUS cell carcinoma
- Publication
Journal of Clinical Medicine, 2023, Vol 12, Issue 23, p7428
- ISSN
2077-0383
- Publication type
Article
- DOI
10.3390/jcm12237428