We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Spinal Cord Involvement in Adult Mitochondrial Diseases: A Cohort Study.
- Authors
Primiano, Guido; Mariotti, Paolo; Turrini, Ida; Sancricca, Cristina; Sabino, Andrea; Torraco, Alessandra; Carrozzo, Rosalba; Servidei, Serenella
- Abstract
The central nervous system is metabolically very demanding and consequently vulnerable to defects of the mitochondrial respiratory chain. While the clinical manifestations and the corresponding radiological findings of the brain involvement in mitochondrial diseases (e.g., stroke-like episodes, signal changes of the basal ganglia, cerebral and cerebellar atrophy) are well known, at present there are few data on the spinal-cord abnormalities in these pathologies, in particular in adult subjects. In this study, we present a cross-sectional cohort study on the prevalence and characterization of spinal-cord involvement in adult patients with genetically defined mitochondrial diseases.
- Subjects
SPINAL cord; MITOCHONDRIA; CENTRAL nervous system; CEREBRAL atrophy; COHORT analysis; NEUROMYELITIS optica
- Publication
Life (2075-1729), 2022, Vol 12, Issue 1, p5
- ISSN
2075-1729
- Publication type
Article
- DOI
10.3390/life12010005