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- Title
Self-Assembled Synthesis and Characterization of Novel [Co(1-vinylimidazole)6].NO3 Polymer: Highly Efficient Antimicrobial Agent.
- Authors
Chang, Fouzia; Memon, Najma; Memon, Shahabuddin; Memon, Ayaz Ali; Bughio, Saddam Hussain; Tahir, Muhammad Nawaz; Chang, Abdul Sattar
- Abstract
Summary: Cobalt coordination polymer i.e. [Co(1-VI)6]•NO3 was successfully synthesized with cobalt metal and (VI = vinylimidazole) and characterized by elemental analysis, FTIR, UV/Vis spectroscopy and X-ray crystallography. The structure of the compound was determined by single X-ray crystallography at temperature 296 K with a Bruker APEX II CCD diffractometer using Mo-Kα radiations (λ = 0.71073 Å), R = 0.0642 and 0.0989. Orthorhombic unit cell parameters are a = 16.1341 (6) Å, b = 16.5179(16) Å, c = 18.2664(16) Å, V= 4868.0 (8) Å, Dx = 4, Mr = 937.91. The X-ray crystallography studies showed that the compound is polymeric in nature, in which cobalt atom coordinated with six N atoms of the 1-vinylimidazole ligands in a distorted orthorhombic geometry. As-prepared compound was screened in vitro against a variety of microorganisms, such as Gram-positive (G +ve) Staphylococcusaureus (S. aureus) and Gram-negative (G-ve) Escherichia coli (E. coli) bacterial strains, and fungal species with Aspergillus niger (A. niger) and Rhizopus stolonifer(R.stolonifer)by applying disk diffusion method. MIC (minimum inhibitory concentration) value for prepared [Co(1-VI)6]•NO3 compound is 125 µg.mL-1a this MIC value cobalt polymer showed higher activity against E. coli and S. aureus () as compared to fungi including; R. StoloniferandA. Niger at 125 µg.mL-1).This study helps to reduce the risk of infectious diseases caused by various microorganisms.
- Subjects
NIGER; COORDINATION polymers; ANTIMICROBIAL polymers; X-ray crystallography; ANTI-infective agents; POLYMERS; ASPERGILLUS niger; UNIT cell
- Publication
Journal of the Chemical Society of Pakistan, 2021, Vol 43, Issue 6, p706
- ISSN
0253-5106
- Publication type
Article
- DOI
10.52568/000973/jcsp/43.06.2021