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- Title
The effect of cytochalasin B and vinca alkaloids on EA- and EAC- rosette formation and on the binding of heat-aggregated human IgG by human lymphocytes.
- Authors
Gutierrez, Carmen; Papamichail, M.; Page Faulk, W.
- Abstract
We report the effect of cytochalasin B and vinca alkaloids on EA- and EAC-rosette formation and on the binding of heat-aggregated human IgG by human lymphocytes. Cytochalasin B inhibits EA- but not EAC-rosette formation, and neither colchicine nor vinblastine have a measurable effect on either reaction. Also, cytochalasin B inhibits the binding of heat-aggregated IgG by human lymphocytes. The inhibition caused by cytochalasin B is reversible, and the cells recover to normal values within 30 min.
- Subjects
CYTOCHALASINS; ANTIBIOTICS; ALKALOIDS; IMMUNOGLOBULIN G; COLCHICINE; LYMPHOCYTES
- Publication
Clinical & Experimental Immunology, 1976, Vol 23, Issue 2, p258
- ISSN
0009-9104
- Publication type
Article