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- Title
Hastanede Yatan Akut Bronşiolit Tanılı Süt Çocuklarında Viral Etiyoloji ve Klinik Seyre Etkisi.
- Authors
Kanık, Ali; Eliaçık, Kayı; Koyun, Begüm; İnce, Osman Tolga; Derici, Yeşer Karaca; Yılmaz, Nisel Özkalay; Çiftdoğan, Dilek Yılmaz
- Abstract
Objective: It was aimed to determine the viral agents in hospitalized infants with acute bronchiolitis and to evaluate the association between clinical course and these agents. Material and Methods: This study was carried out with the retrospective review of 177 patients aged 1 month-2 years old who were hospitalized in İzmir Tepecik Teaching Hospital between October 2014 and May 2015 due to acute bronchiolitis. Nasopharyngeal swab samples were examined for respiratory sinsitial virus (RSV) A+B, rhinovirus, influenzae virus A+B, parainfluenzae virus 1, 2, 3 and 4, human metapneu- mo virus, adenovirus, coronavirus OCD43, 229E and NL63, bocavirus and enterovirus with "Multiplex Polymerase chain reaction" (M-PCR) method. The relationship was evaluated between the determinated agents and the demographic, clinic, laboratory features and the hospitalization period. Results: Among the 177 patients who were included in the study, in 159 (89.8%) at least one agent was detected by using M-PCR method. The mean age of these 159 patients was 6.27 ± 5.10 months and 109 (68.6%) were male. 282 agents were detected. While in 88 (55.3%) cases a single virus were detected, in 71 (44.7%) multipl virus were determined. In the evalutaion of both single and multipl agents group, RSV was the most common virus (n=101, 57.1%). It was followed by 48 (27.1%) rinovirus and 23 (13.0%) influenzae virus. While the inital clinical scores were the highest in adenovirus infection, there was no difference between the other viral infections with single or multiple agents in terms of initial clinical scores and hospitalization period. Conclusion: Despite the new diagnostic methods of variable viruses, RSV is still continuing with high ratios in the hospitalized infants with acute bronchiolitis. In this study no significant association was detected between the clinical features and the viral agents.
- Subjects
TURKEY; ACADEMIC medical centers; BIOMARKERS; HOSPITAL care of newborn infants; POLYMERASE chain reaction; RESPIRATORY syncytial virus; VIRUS diseases; BRONCHIOLE diseases; RETROSPECTIVE studies; SEASONAL influenza
- Publication
Journal of Pediatric Infection / Çocuk Enfeksiyon Dergisi, 2016, Vol 10, Issue 3, p93
- ISSN
1307-1068
- Publication type
Article
- DOI
10.5152/ced.2016.2425