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- Title
«Real-life»-Daten zur Asthma-kontrolle mit Budesonid/Formoterol als Erhaltungs- und Bedarfstherapie: die Erfahrung in der Schweiz.
- Authors
Steurer-Stey, C.; Courteheuse, C.; Taegtmeyer, A. B.; Leuppi, J. D.
- Abstract
Background: Asthma is not adequately controlled in many patients. A new approach in asthma treatment, known as Budesonide/Formoterol Maintenance and Reliever Therapy has shown improvement in asthma control compared to conventional therapy regimens. As Switzerland was the first European country to formally approve budesonide/formoterol maintenance and reliever therapy, a patient follow-up programme was commenced in January 2006 to investigate its efficacy and safety in a «real-life» environment. Methods: A non randomised uncontrolled post-marketing survey involving 420 physicians in all language regions in Switzerland was carried out. 2035 patients with asthma were enrolled. Data on current asthma treatment, asthma control and unscheduled visits due to worsening asthma were recorded. Asthma control was assessed subjectively by both the patients and the physicians as well as by means of the validated 5-item Asthma Control Questionnaire (ACQ5). An ACQ score of 0.75 or less indicates well-controlled asthma. Results: Data from 2006 out of 2035 patients were analysed (mean age 44.9 ± 19.6 years, 50.5% female). With budesonide/formoterol maintenance and reliever therapy the mean ACQ5 score improved by more than 3-fold the defined minimal important difference (MID). The percentage of patients with an ACQ score ≤0.75 increased from 4.8% at baseline to 58.0% at the end of the follow-up programme. Patient satisfaction with budesonide/formoterol for both maintenance and relief was high. Conclusions: Budesonide/formoterol maintenance and reliever therapy improves asthma control in a non randomised real-life setting.
- Subjects
SWITZERLAND; ASTHMA treatment; ANTIASTHMATIC agents; FORMOTEROL; DRUG efficacy
- Publication
Praxis (16618157), 2009, Vol 98, Issue 23, p1335
- ISSN
1661-8157
- Publication type
Article
- DOI
10.1024/1661-8157.98.23.1335