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- Title
Pancreatic serous cystoadenoma (CSA) showing increased tracer uptake at 68-GaDOTA-peptide Positron Emission Tomography (68Ga-DOTA-peptide PET-CT): a case report.
- Authors
Nappo, Gennaro; Funel, Niccola; Giudici, Simone; Spaggiari, Paola; Capretti, Giovanni; Carrara, Silvia; Pepe, Giovanna; Zerbi, Alessandro
- Abstract
<bold>Background: </bold>Serous cysto-adenoma (SCA) is a rare benign neoplasm of the pancreas. SCA can mimic other pancreatic lesions, such as neuroendocrine tumours. 68Gallium-DOTA-peptide Positron Emission Tomography (PET) is able to image in vivo the over-expression of the somatostatin receptors, playing an important role for the identification of neuroendocrine neoplasms.<bold>Case Presentation: </bold>We reported a case of 63-year-old man, with a solid lesion of 7 cm of diameter of the body-tail of the pancreas. Two fine-needle-aspirations (FNA) were inconclusive. A 68Ga-DOTA-peptide PET-CT revealed a pathological uptake of the pancreatic lesion. The diagnosis of a pancreatic neuroendocrine neoplasm was established and a laparoscopic distal splenopancreatectomy and cholecystectomy was performed. Final histopathological report revealed the presence of a micro-cystic SCA.<bold>Conclusions: </bold>The current case firstly reports a pancreatic SCA showing increased radiopharmaceutical uptake at 68Ga-DOTA-peptide PET-CT images. This unexpected finding should be taken into account during the diagnostic algorithm of a pancreatic lesion, in order to minimize the risk of misdiagnosis and overtreatment of SCA.
- Subjects
POSITRON emission tomography computed tomography; SOMATOSTATIN receptors; BENIGN tumors; CHOLECYSTITIS; PANCREATIC tumors; LAPAROSCOPIC surgery
- Publication
BMC Surgery, 2020, Vol 20, Issue 1, p1
- ISSN
1471-2482
- Publication type
journal article
- DOI
10.1186/s12893-020-01004-2