We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Enhancing Flexible Neural Probe Performance via Platinum Deposition: Impedance Stability under Various Conditions and In Vivo Neural Signal Monitoring.
- Authors
Park, Daerl; Jeong, Hyeonyeong; Choi, Jungsik; Han, Juyeon; Piao, Honglin; Kim, Jaehyun; Park, Seonghoon; Song, Mingu; Kim, Dowoo; Sung, Jaesuk; Cheong, Eunji; Choi, Heonjin
- Abstract
Monitoring neural activity in the central nervous system often utilizes silicon-based microelectromechanical system (MEMS) probes. Despite their effectiveness in monitoring, these probes have a fragility issue, limiting their application across various fields. This study introduces flexible printed circuit board (FPCB) neural probes characterized by robust mechanical and electrical properties. The probes demonstrate low impedance after platinum coating, making them suitable for multiunit recordings in awake animals. This capability allows for the simultaneous monitoring of a large population of neurons in the brain, including cluster data. Additionally, these probes exhibit no fractures, mechanical failures, or electrical issues during repeated-bending tests, both during handling and monitoring. Despite the possibility of using this neural probe for signal measurement in awake animals, simply applying a platinum coating may encounter difficulties in chronic tests and other applications. Furthermore, this suggests that FPCB probes can be advanced by any method and serve as an appropriate type of tailorable neural probes for monitoring neural systems in awake animals.
- Subjects
FLEXIBLE printed circuits; MECHANICAL failures; CENTRAL nervous system; MICROELECTROMECHANICAL systems; PLATINUM
- Publication
Micromachines, 2024, Vol 15, Issue 8, p1058
- ISSN
2072-666X
- Publication type
Article
- DOI
10.3390/mi15081058