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- Title
Immune-related intestinal pseudo-obstruction caused by immune checkpoint inhibitors: case report.
- Authors
Yimeng Qian; Zheng Zhi; Jing Ai; Lin Kang; Gang Qiu; Xin Huang; Jing Zhao
- Abstract
Intestinal obstruction, a rare manifestation of immunotherapy-related gastrointestinal adverse events, can be severe and even life-threatening with intestinal perforation. We present a 64-year-old man with HCC and currently under the therapy with Pembrolizumab, who was admitted in our hospital with abdominal distension. Radiologic findings were consistent with small bowel ileus. After conservative treatment, the patient underwent colonoscopy where no cause of ileus was discovered. The patient received high-dose prednisone due to the side effects of immune checkpoint inhibitor therapy. This resulted in a gradual improvement of symptoms.
- Subjects
IMMUNE checkpoint inhibitors; BOWEL obstructions; SMALL intestine; CONSERVATIVE treatment; PREDNISONE
- Publication
Frontiers in Oncology, 2024, p01
- ISSN
2234-943X
- Publication type
Article
- DOI
10.3389/fonc.2024.1415117