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- Title
Sibutramin Etkinliğinin Psikopatoloji ve Yeme Patolojisi İle İliğkisi.
- Authors
Akalın, Aysen; Yazıcı, Fadime; Erol, Atila
- Abstract
Objective: Sibutramin is a drug used in the treatment of obesity through its effects on central nervous system. The relation between obesity and psycopathology and eating pathologies were shown in multiple trials. But the effects of sibutramin on general psycopathology and on eating pathologies have not been studied. In this study, the relation between sibutramin effect and general psycopathology and signs of eating pathologies were investigated. Methods: SCL-90-R (Symtom Check List), EAT (Eating Attitude Test) and BITE (Bulimic Investigatigatory Test Edinbourg), RSES (Rosenberg Self-esteem Scale) and BDI (Beck Depression Inventory) were applied to 26 female patients whom applied for teatment of obesity to Eskişehir Osmangazi University Medical Faculty Endocrinology Outpatient Department. They were prescribed Sibutramin 10 mg/d along with low caloric diets for 6 months. Weights of the patients were recorded before and after 6 months of Sibutramin treatment. Results: After Sibutramin treatment patients lost 9.5% of their initial weights. Their initial mean BMI (body mas index) was 36.79 and the mean BMI obtained after the treatment was 33.30. The weight obtained after the treatment was significantly lower than the initial weights of the patients (p<0.01). Although the eating pathology scores of the patients were high (EAT: mean 29; BITE symptom:11.9; SD:3.4; BITE severity mean 4.43; SD:3.02), there was no statistically significant correlation between weight lost with Sibutramin treatment and general psycopathology (r:0.15; p<0.05), BITE (r:0.1;p<0.05) and EAT (r:0.22; p<0.05) scores. No correlation was found between the decreament in body mass indices with the same variables. Conclusion: Findings were in support of the efficacy of Sibutramin treatment on obesity treatment and it is concluded that the effect of Sibutramin was independent of general psycopathology and eating pathologies.
- Subjects
SIBUTRAMINE; PATHOLOGICAL psychology; OBESITY; CENTRAL nervous system abnormalities; BECK Depression Inventory
- Publication
Klinik Psikofarmakoloji Bulteni, 2009, Vol 19, pS275
- ISSN
1017-7833
- Publication type
Article