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- Title
Comparison of four commercial SARS-CoV-2 IgG immuno-assays in RT-PCR negative patients with suspect CT findings.
- Authors
Van Praet, Jens T.; Coene, Ann-Sofie; Van De Moortele, Kris; Descheemaeker, Patrick; Reynders, Marijke
- Abstract
A subset of patients with Covid-19 presents with negative RT-PCR screening but suspect CT findings. Using four commercially available anti-SARS-CoV-2 IgG immuno-assays, we found this subset constituted 9.2% of all consecutively admitted outpatients with Covid-19 in our hospital. Clinical specificity for Covid-19 of some N protein-based immuno-assays was suboptimal, as positive results were observed in control patients with recent common human coronavirus, influenza B and adenovirus infections.
- Subjects
ADENOVIRUSES; COMPARATIVE studies; COMPUTED tomography; IMMUNOASSAY; IMMUNOGLOBULINS; POLYMERASE chain reaction; SERODIAGNOSIS; REVERSE transcriptase polymerase chain reaction; INFLUENZA B virus; COVID-19; SARS-CoV-2
- Publication
Infection, 2021, Vol 49, Issue 1, p145
- ISSN
0300-8126
- Publication type
Article
- DOI
10.1007/s15010-020-01523-3