We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Familial syndromes associated with intracranial tumours: a review.
- Authors
Ranger, Adrianna; Patel, Yatri; Chaudhary, Navjot; Anantha, Ram
- Abstract
Background: Most cancers of the central nervous system (CNS) occur sporadically in the absence of any known underlying familial disorder or multi-systemic syndrome. Several syndromes are associated with CNS malignancies, however, and their recognition has significant implications for patient management and prognosis. Patients with syndrome-associated CNS malignancies often have multiple tumours (either confined to one region or distributed throughout the body), with similar or different histology. Objective: This review examines syndromes that are strongly associated with CNS cancers: the phakomatosis syndromes, familial syndromes such as Li-Fraumeni and familial polyposis syndromes and dyschondroplasia.
- Subjects
CENTRAL nervous system cancer; CANCER patients; ADENOMATOUS polyposis coli; PROGNOSIS; HISTOLOGICAL techniques
- Publication
Child's Nervous System, 2014, Vol 30, Issue 1, p47
- ISSN
0256-7040
- Publication type
Article
- DOI
10.1007/s00381-013-2309-z